[HTML][HTML] Promising therapeutic targets for treatment of rheumatoid arthritis

J Huang, X Fu, X Chen, Z Li, Y Huang… - Frontiers in …, 2021 - frontiersin.org
Rheumatoid arthritis (RA) is a systemic poly-articular chronic autoimmune joint disease that
mainly damages the hands and feet, which affects 0.5% to 1.0% of the population …

Long non-coding RNA: Classification, biogenesis and functions in blood cells

S Dahariya, I Paddibhatla, S Kumar… - Molecular …, 2019 - Elsevier
While there exist some long non-coding RNAs (lncRNAs) that are structurally similar to
mRNAs (capped, spliced, poly a tail), not all of the lncRNAs exhibit these features …

[HTML][HTML] Linking a role of lncRNAs (long non-coding RNAs) with insulin resistance, accelerated senescence, and inflammation in patients with type 2 diabetes

C Sathishkumar, P Prabu, V Mohan… - Human genomics, 2018 - Springer
Background Studying epigenetics is expected to provide precious information on how
environmental factors contribute to type 2 diabetes mellitus (T2DM) at the genomic level …

[HTML][HTML] Long noncoding RNAs and circular RNAs in autoimmune diseases

V Lodde, G Murgia, ER Simula, M Steri, M Floris… - Biomolecules, 2020 - mdpi.com
Immune responses are essential for the clearance of pathogens and the repair of injured
tissues; however, if these responses are not properly controlled, autoimmune diseases can …

[HTML][HTML] Long non-coding RNA HIX003209 promotes inflammation by sponging miR-6089 via TLR4/NF-κB signaling pathway in rheumatoid arthritis

S Yan, P Wang, J Wang, J Yang, H Lu, C Jin… - Frontiers in …, 2019 - frontiersin.org
Accumulating studies have suggested that long non-coding RNAs (lncRNAs) have drawn
more and more attention in rheumatoid arthritis (RA), which can function as competitive …

[HTML][HTML] Lnc-ITSN1-2, derived from RNA sequencing, correlates with increased disease risk, activity and promotes CD4+ T cell activation, proliferation and Th1/Th17 …

J Nie, Q Zhao - Frontiers in immunology, 2020 - frontiersin.org
Background: This study aimed to investigate long-non-coding RNA (lncRNA) expression
profiles and the correlation of lnc-ITSN1-2 expression with disease risk, activity and …

[HTML][HTML] The role of non-coding RNAs (miRNA and lncRNA) in the clinical management of rheumatoid arthritis

J Yang, Z Li, L Wang, X Yun, Y Zeng, JPL Ng… - Pharmacological …, 2022 - Elsevier
Rheumatoid arthritis (RA) is a chronic systemic inflammatory disorder which is associated
with the dysregulation of autoimmune response. In recent years, early diagnosis, aggressive …

[HTML][HTML] Functional interactions between lncRNAs/circRNAs and miRNAs: insights into rheumatoid arthritis

JJ Han, XQ Wang, XA Zhang - Frontiers in Immunology, 2022 - frontiersin.org
Rheumatoid arthritis (RA) is one of the most common autoimmune diseases that affect
synovitis, bone, cartilage, and joint. RA leads to bone and cartilage damage and extra …

Long noncoding RNA/circular RNA regulates competitive endogenous RNA networks in rheumatoid arthritis: molecular mechanisms and traditional Chinese medicine …

J Wen, J Liu, L Wan, F Wang - Annals of Medicine, 2023 - Taylor & Francis
Rheumatoid arthritis (RA) is a systemic and autoimmune disease that is mainly featured
abnormal fibroblast-like synoviocyte (FLS) proliferation and inflammatory cell infiltration …

RNA-seq reveals the circular RNA and miRNA expression profile of peripheral blood mononuclear cells in patients with rheumatoid arthritis

J Wen, J Liu, P Zhang, H Jiang, L Xin, L Wan… - Bioscience …, 2020 - portlandpress.com
Abstract Objective: Circular RNAs (circRNAs) are a significant class of molecules involved in
a wide range of diverse biological functions that are abnormally expressed in many types of …