Lipid–protein interactions in virus assembly and budding from the host cell plasma membrane

BB Motsa, RV Stahelin - Biochemical Society Transactions, 2021 - portlandpress.com
Lipid enveloped viruses contain a lipid bilayer coat that protects their genome to help
facilitate entry into the new host cell. This lipid bilayer comes from the host cell which they …

[HTML][HTML] Role of phosphatidic acid lipids on plasma membrane association of the Ebola virus matrix protein VP40

MD Cioffi, ML Husby, BS Gerstman, RV Stahelin… - … et Biophysica Acta (BBA …, 2024 - Elsevier
The Ebola virus matrix protein VP40 is responsible for the formation of the viral matrix by
localizing at the inner leaflet of the human plasma membrane (PM). Various lipid types …

A conserved tryptophan in the Ebola virus matrix protein C-terminal domain is required for efficient virus-like particle formation

KA Johnson, R Pokhrel, MR Budicini, BS Gerstman… - Pathogens, 2020 - mdpi.com
The Ebola virus (EBOV) harbors seven genes, one of which is the matrix protein eVP40, a
peripheral protein that is sufficient to induce the formation of virus-like particles from the host …

Identification of novel inhibitors against VP40 protein of Marburg virus by integrating molecular modeling and dynamics approaches

M Saeed, MA Alamri, MAR Rashid… - Journal of …, 2023 - Taylor & Francis
Marburg virus (MV) is a highly etiological agent of haemorrhagic fever in humans and has
spread across the world. Its outbreaks caused a 23–90% human death rate. However, there …

The minor matrix protein VP24 from Ebola virus lacks direct lipid-binding properties

Y Su, RV Stahelin - Viruses, 2020 - mdpi.com
Viral protein 24 (VP24) from Ebola virus (EBOV) was first recognized as a minor matrix
protein that associates with cellular membranes. However, more recent studies shed light on …

Analysis of Marburg Virus Protein Interactions

VJ Heintz - 2022 - search.proquest.com
Infection by Marburgvirus (MARV) or the closely related Ebolavirus (EBOV) results in
potentially lethal hemorrhagic fever in humans characterized by uncontrolled viremia, a …

Identification of the Functional Domain of HPIV3 Matrix Protein Interacting with Nucleocapsid Protein

X Deng, C Zhang, K Zhang, N Lu, Y He… - BioMed Research …, 2020 - Wiley Online Library
Human parainfluenza virus type 3 (HPIV3) is the main pathogen that causes respiratory
infections in infants, young children, and the elderly. Currently, there are no vaccines and …