Isolation, cultivation, and characterization of human mesenchymal stem cells

D Mushahary, A Spittler, C Kasper, V Weber… - Cytometry Part …, 2018 - Wiley Online Library
Mesenchymal stem cells (MSC) exhibit a high self‐renewal capacity, multilineage
differentiation potential and immunomodulatory properties. This set of exceptional features …

Explant culture: An advantageous method for isolation of mesenchymal stem cells from human tissues

F Hendijani - Cell proliferation, 2017 - Wiley Online Library
Mesenchymal stem cell (MSC) research progressively moves towards clinical phases.
Accordingly, a wide range of different procedures were presented in the literature for MSC …

Wharton's jelly derived mesenchymal stem cells: future of regenerative medicine? Recent findings and clinical significance

I Kalaszczynska, K Ferdyn - BioMed research international, 2015 - Wiley Online Library
Around 5 million annual births in EU and 131 million worldwide give a unique opportunity to
collect lifesaving Wharton's jelly derived mesenchymal stem cells (WJ‐MSC). Evidences that …

Mesenchymal stem cells in preclinical cancer cytotherapy: a systematic review

I Christodoulou, M Goulielmaki, M Devetzi… - Stem Cell Research & …, 2018 - Springer
Mesenchymal stem cells (MSC) comprise a heterogeneous population of rapidly
proliferating cells that can be isolated from adult (eg, bone marrow, adipose tissue) as well …

Human Wharton's jelly—cellular specificity, stemness potency, animal models, and current application in human clinical trials

K Stefańska, K Ożegowska, G Hutchings… - Journal of Clinical …, 2020 - mdpi.com
Stem cell therapies offer a great promise for regenerative and reconstructive medicine, due
to their self-renewal and differentiation capacity. Although embryonic stem cells are …

Optimization of human umbilical cord mesenchymal stem cell isolation and culture methods

YF Han, R Tao, TJ Sun, JK Chai, G Xu, J Liu - Cytotechnology, 2013 - Springer
Human umbilical cord mesenchymal stem cells (hUCMSCs) are considered to be an ideal
replacement for bone marrow MSCs. However, up to date, there is no convenient and …

Therapeutic efficacy of umbilical cord-derived mesenchymal stem cells in patients with type 2 diabetes

LX Guan, H Guan, HB Li, CA Ren… - Experimental and …, 2015 - spandidos-publications.com
Abstract Type 2 diabetes (T2D) is characterized by progressive and inexorable β‑cell
dysfunction, leading to insulin deficiency. Novel strategies to preserve the remaining β‑cells …

[HTML][HTML] Isolation and characterisation of mesenchymal stem cells derived from human placenta tissue

S Vellasamy, P Sandrasaigaran… - World journal of stem …, 2012 - ncbi.nlm.nih.gov
AIM: To explore the feasibility of placenta tissue as a reliable and efficient source for
generating mesenchymal stem cells (MSC). METHODS: MSC were generated from human …

Mesenchymal cells in the treatment of spinal cord injury: current & future perspectives

R Vawda, MG Fehlings - Current stem cell research & therapy, 2013 - ingentaconnect.com
Nearly 1.5 million people in the US live with a spinal cord injury (SCI). The cost to the
healthcare system is estimated at over $10 billion annually likely because over 65% of SCIs …

Mesenchymal stem/progenitor cells: the prospect of human clinical translation

D Rady, MMS Abbass, AA El-Rashidy… - Stem Cells …, 2020 - Wiley Online Library
Mesenchymal stem/progenitor cells (MSCs) are key players in regenerative medicine,
relying principally on their differentiation/regeneration potential, immunomodulatory …