Background Platelets with high hemostatic activity play an important role in the
pathophysiology of coronary artery disease (CAD) and mean platelet volume (MPV) has …

There has been much recent interest in the role of the vitamin D axis in lung disease, which
includes vitamin D, vitamin D receptor (VDR) and vitamin D-binding protein (VDBP; also …

BACKGROUND: The discovery of filaggrin (FLG) null mutations as a major risk factor for
eczema represents a milestone toward the understanding of an important mechanism in this …

BACKGROUND: There is an increasing recognition that the pathophysiology of mental
disorders could be the result of deregulation of synaptic plasticity with alterations of …

Background: Polymorphisms of interleukin-1B (IL1B) and its receptor antagonist (IL1RN)
genes have been inconsistently associated with gastric cancer risk. We examined these …

We conducted a meta-analysis to assess the association between patatin-like
phospholipase domain-containing 3 (PNPLA3) rs738409 polymorphism and nonalcoholic …

BACKGROUND: With an impressive series of replication studies, filaggrin (FLG) has
become the gene with the most widely replicated association to atopic eczema (AE) …

Age-related macular degeneration (AMD) is the leading cause of blindness in the developed
world and complement factor H (CFH) polymorphism has been found to associated with the …

Background Neural Tube Defects (NTDs) are among the most prevalent and most severe
congenital malformations worldwide. Polymorphisms in key genes involving the folate …

Rationale: The comprehensive evaluation of gene variation, haplotype structure, and
linkage disequilibrium is important in understanding the function of β2-adrenergic receptor …