Respiration is a brain function on which our lives essentially depend. Control of respiration
ensures that the frequency and depth of breathing adapt continuously to metabolic needs. In …

Cerebellar research has focused principally on adult motor function. However, the
cerebellum also maintains abundant connections with nonmotor brain regions throughout …

Making inferences about the computations performed by neuronal circuits from synapse-
level connectivity maps is an emerging opportunity in neuroscience. The mushroom body …

The human brain contains approximately 60 billion cerebellar granule cells, which
outnumber all other brain neurons combined. Classical theories posit that a large, diverse …

The human cerebellum has a protracted developmental timeline compared with the
neocortex, expanding the window of vulnerability to neurological disorders. As the …

Synaptic connectivity varies widely across neuronal types. Cerebellar granule cells receive
five orders of magnitude fewer inputs than the Purkinje cells they innervate, and cerebellum …

Neural circuits for essential natural behaviors are shaped by selective pressure to
coordinate reliable execution of flexible goal-directed actions. However, the structural and …

The cerebellum has long been proposed to play a role in cognitive function, although this
has remained controversial. This idea has received renewed support with the recent …

When animals interact with complex environments, their neural circuits must separate
overlapping patterns of activity that represent sensory and motor information. Pattern …

The cerebellar cortex has a key role in generating predictive sensorimotor associations. To
do so, the granule cell layer is thought to establish unique sensorimotor representations for …