The use of alternative strategies for enhanced nanoparticle delivery to solid tumors

M Izci, C Maksoudian, BB Manshian… - Chemical …, 2021 - ACS Publications
Nanomaterial (NM) delivery to solid tumors has been the focus of intense research for over a
decade. Classically, scientists have tried to improve NM delivery by employing passive or …

Photodynamic therapy for cancer: what's past is prologue

MR Hamblin - Photochemistry and photobiology, 2020 - Wiley Online Library
Abstract Thomas J Dougherty from Roswell Park Cancer Center played a major role in the
progress of photodynamic therapy (PDT) from a laboratory science into a real‐world clinical …

The role of porphyrin chemistry in tumor imaging and photodynamic therapy

M Ethirajan, Y Chen, P Joshi, RK Pandey - Chemical Society Reviews, 2011 - pubs.rsc.org
In recent years several review articles and books have been published on the use of
porphyrin-based compounds in photodynamic therapy (PDT). This critical review is focused …

Imaging and photodynamic therapy: mechanisms, monitoring, and optimization

JP Celli, BQ Spring, I Rizvi, CL Evans… - Chemical …, 2010 - ACS Publications
The purpose of this review is to present the current state of the role of imaging in
photodynamic therapy (PDT). For the reader to fully appreciate the context of the discussions …

Photodynamic therapy

TJ Dougherty, CJ Gomer, BW Henderson… - Journal of National …, 1998 - academic.oup.com
Photodynamic therapy involves administration of a tumorlocalizing photosensitizing agent,
which may require metabolic synthesis (ie, a prodrug), followed by activation of the agent by …

Oncologic photodynamic therapy photosensitizers: a clinical review

RR Allison, CH Sibata - Photodiagnosis and photodynamic therapy, 2010 - Elsevier
A myriad of naturally occurring and synthetic structures are capable of transferring the
energy of light. Few, however, allow for this energy transfer to enable a type II photochemical …

Basic principles of photodynamic therapy

IJ Macdonald, TJ Dougherty - Journal of porphyrins and …, 2001 - World Scientific
The therapeutic use of light, as we know it, begins in 1900 when Raab reported that the
combination of acridine orange and light could destroy living organisms (paramecium)[1]. In …

Nanoparticles as vehicles for delivery of photodynamic therapy agents

D Bechet, P Couleaud, C Frochot, ML Viriot… - Trends in …, 2008 - cell.com
Photodynamic therapy (PDT) in cancer treatment involves the uptake of a photosensitizer by
cancer tissue followed by photoirradiation. The use of nanoparticles as carriers of …

Ceramic-based nanoparticles entrapping water-insoluble photosensitizing anticancer drugs: A novel drug− carrier system for photodynamic therapy

I Roy, TY Ohulchanskyy, HE Pudavar… - Journal of the …, 2003 - ACS Publications
A novel nanoparticle-based drug carrier for photodynamic therapy is reported which can
provide stable aqueous dispersion of hydrophobic photosensitizers, yet preserve the key …

Digestion, absorption, and cancer preventative activity of dietary chlorophyll derivatives

MG Ferruzzi, J Blakeslee - Nutrition research, 2007 - Elsevier
The growing body of epidemiological and experimental evidence associating diets rich in
fruits and vegetables with prevention of chronic diseases such as cancer has stimulated …