Melatonin and its metabolites vs oxidative stress: From individual actions to collective protection
Oxidative stress (OS) represents a threat to the chemical integrity of biomolecules including
lipids, proteins, and DNA. The associated molecular damage frequently results in serious …
lipids, proteins, and DNA. The associated molecular damage frequently results in serious …
Free radicals and polyphenols: The redox chemistry of neurodegenerative diseases
S Losada-Barreiro, C Bravo-Diaz - European journal of medicinal chemistry, 2017 - Elsevier
The oxidation of bioorganic materials by air and, particularly, the oxidative stress involved in
the cell loss and other pathologies associated with neurodegenerative diseases (NDs) are …
the cell loss and other pathologies associated with neurodegenerative diseases (NDs) are …
Black phosphorus nanosheets as a neuroprotective nanomedicine for neurodegenerative disorder therapy
W Chen, J Ouyang, X Yi, Y Xu, C Niu… - Advanced …, 2018 - Wiley Online Library
Transition‐metal dyshomeostasis is recognized as a critical pathogenic factor at the onset
and progression of neurodegenerative disorder (ND). Excess transition‐metal ions such as …
and progression of neurodegenerative disorder (ND). Excess transition‐metal ions such as …
Recent progress in the identification of selective butyrylcholinesterase inhibitors for Alzheimer's disease
Q Li, H Yang, Y Chen, H Sun - European journal of medicinal chemistry, 2017 - Elsevier
Alzheimer's disease (AD) is one of the most prevalent neurodegenerative disorders with
notable factor of dysfunction in cholinergic system. Low ACh level can be observed in the …
notable factor of dysfunction in cholinergic system. Low ACh level can be observed in the …
Computational strategies for predicting free radical scavengers' protection against oxidative stress: where are we and what might follow?
A Galano, J Raúl Alvarez‐Idaboy - International Journal of …, 2019 - Wiley Online Library
Oxidative stress, which is frequently induced by an overproduction of free radicals (FR),
poses a high risk to human health. Thus, finding efficient strategies for scavenging FR is a …
poses a high risk to human health. Thus, finding efficient strategies for scavenging FR is a …
Multitarget therapeutic strategies for Alzheimer's disease: Review on emerging target combinations
Neurodegenerative diseases represent nowadays one of the major health problems.
Despite the efforts made to unveil the mechanism leading to neurodegeneration, it is still not …
Despite the efforts made to unveil the mechanism leading to neurodegeneration, it is still not …
Curcumin in health and diseases: Alzheimer's disease and curcumin analogues, derivatives, and hybrids
E Chainoglou, D Hadjipavlou-Litina - International journal of molecular …, 2020 - mdpi.com
Worldwide, Alzheimer's disease (AD) is the most common neurodegenerative multifactorial
disease influencing the elderly population. Nowadays, several medications, among them …
disease influencing the elderly population. Nowadays, several medications, among them …
[HTML][HTML] Successful therapies for Alzheimer's disease: why so many in animal models and none in humans?
R Franco, A Cedazo-Minguez - Frontiers in pharmacology, 2014 - frontiersin.org
Peering into the field of Alzheimer's disease (AD), the outsider realizes that many of the
therapeutic strategies tested (in animal models) have been successful. One also may notice …
therapeutic strategies tested (in animal models) have been successful. One also may notice …
Neuroprotective effects of bioavailable polyphenol-derived metabolites against oxidative stress-induced cytotoxicity in human neuroblastoma SH-SY5Y cells
A González-Sarrías, MA Núñez-Sánchez… - Journal of agricultural …, 2017 - ACS Publications
Oxidative stress is involved in cell death in neurodegenerative diseases. Dietary
polyphenols can exert health benefits, but their direct effects on neuronal cells are debatable …
polyphenols can exert health benefits, but their direct effects on neuronal cells are debatable …
Dancing with reactive oxygen species generation and elimination in nanotheranostics for disease treatment
Reactive oxygen species (ROS) play important roles in cell signaling and tissue
homeostasis, in which the level of ROS is critical through the equilibrium between ROS …
homeostasis, in which the level of ROS is critical through the equilibrium between ROS …