Epithelial–mesenchymal transition (EMT) is a cellular programme that is known to be crucial
for embryogenesis, wound healing and malignant progression. During EMT, cell–cell and …

Metastasis is the major cause of cancer-related deaths; therefore, the prevention and
treatment of metastasis are fundamental to improving clinical outcomes. Epithelial …

Cancer metastasis and therapy resistance are the major unsolved clinical challenges, and
account for nearly all cancer-related deaths. Both metastasis and therapy resistance are …

Epithelial‐to‐mesenchymal transition (EMT) and its reverse mesenchymal‐to‐epithelial
transition (MET) have been suggested to play crucial roles in metastatic dissemination of …

Abstract The CellSearch® system (CS) enables standardized enrichment and enumeration
of circulating tumor cells (CTCs) that are repeatedly assessable via non-invasive “liquid …

Elucidating the spectrum of epithelial-mesenchymal transition (EMT) and mesenchymal-
epithelial transition (MET) states in clinical samples promises insights on cancer progression …

The concept of differentiation therapy emerged from the fact that hormones or cytokines may
promote differentiation ex vivo, thereby irreversibly changing the phenotype of cancer cells …

Abstract Changes in cell adhesion and motility are considered key elements in determining
the development of invasive and metastatic tumors. Co-opting the epithelial-to …

The mechanism of epithelial-mesenchymal transition (EMT) consists of the cellular
phenotypic transition from epithelial to mesenchymal status. The cells exhibiting EMT exist in …

Chemoresistance remains a major complication of cancer treatments. Recent data provide
strong evidence that chemoresistance is linked to epithelial–mesenchymal transition (EMT) …