Copper is one of the most abundant basic transition metals in the human body. It takes part
in oxygen metabolism, collagen synthesis, and skin pigmentation, maintaining the integrity …

Homocysteine (Hcy) is a sulfur-containing non-proteinogenic amino acid derived in
methionine metabolism. The increased level of Hcy in plasma, hyperhomocysteinemia, is …

Folate receptors (FRα, FRβ and FRγ) are cysteine-rich cell-surface glycoproteins that bind
folate with high affinity to mediate cellular uptake of folate. Although expressed at very low …

Background It has been reported that neural tube defects (NTD) can be prevented with
periconceptional folic acid supplementation. The effects of different doses, forms and …

Aneuploidy (trisomy or monosomy) is the most commonly identified chromosome
abnormality in humans, occurring in at least 5% of all clinically recognized pregnancies …

Common strategies to decide whether a variable is a confounder that should be adjusted for
in the analysis rely mostly on statistical criteria. The authors present findings from the Slone …

Neural tube defects (NTDs) are common complex congenital malformations resulting from
failure of the neural tube closure during embryogenesis. It is established that folic acid …

Folate being an important vitamin of B Complex group in our diet plays an important role not
only in the synthesis of DNA but also in the maintenance of methylation reactions in the …

Major efforts have been directed at family-based association and case–control studies to
identify the involvement of candidate genes in the major disorders of mental health. What …

Male infertility is a multifactorial complex disease with highly heterogeneous phenotypic
representation and in at least 15% of cases, this condition is related to known genetic …