The brain has almost no energy reserve, but its activity coordinates organismal function, a
burden that requires precise coupling between neurotransmission and energy metabolism …

The participation of astrocytes in brain computation was hypothesized in 1992, coinciding
with the discovery that these cells display a form of intracellular Ca2+ signaling sensitive to …

We propose and empirically support a parsimonious account of intrinsic, brain-wide
spatiotemporal organization arising from traveling waves linked to arousal. We hypothesize …

Brain computation performed by billions of nerve cells relies on a sufficient and
uninterrupted nutrient and oxygen supply,. Astrocytes, the ubiquitous glial neighbours of …

The integrity of myelinated axons relies on homeostatic support from oligodendrocytes
(OLs). To determine how OLs detect axonal spiking and how rapid axon–OL metabolic …

The mechanisms by which astrocytes modulate neural homeostasis, synaptic plasticity, and
memory are still poorly explored. Astrocytes form large intercellular networks by gap junction …

Genetically encoded fluorescent biosensors are powerful tools used to track chemical
processes in intact biological systems. However, the development and optimization of …

Astrocytes establish extensive networks via gap junctions that allow each astrocyte to
connect indirectly to the vasculature. However, the proportion of astrocytes directly …

Abstract l-Lactate is increasingly appreciated as a key metabolite and signaling molecule in
mammals. However, investigations of the inter-and intra-cellular dynamics of l-lactate are …

Neural computational power is determined by neuroenergetics, but how and which energy
substrates are allocated to various forms of memory engram is unclear. To solve this …