In recent decades, transient and highly reactive ortho-quinodimethanes (o-QDMs), ortho-
quinone methides (o-QMs) and aza-ortho-quinone methides (aza-o-QMs) have attracted …

Cancer is considered as one of the most serious health problems today. The discovery of
nitrogen mustard as an alkylating agent in 1942, opened a new era in the cancer …

The diversity of elements among US Food and Drug Administration (FDA) approved
pharmaceuticals is analyzed and reported, with a focus on atoms other than carbon …

Despite enormous progress in the field of the synthetic chemistry involving, for example,
catalytic and combinatorial synthesis of a large libraries of compounds, multicomponent …

The electron-rich five-membered aromatic aza-heterocyclic imidazole, which contains two
nitrogen atoms, is an important functional fragment widely present in a large number of …

Nowadays, the use of nanostructures in various medical and biological fields such as drug
delivery in cancer treatment is increasing. Among the nanostructures, graphene oxide (GO) …

The first and asymmetric total synthesis of bufogargarizins A and B, two unusual and highly
oxygenated twin steroids with rearranged A/B rings, was achieved. The synthetically …

Diosgenin, a naturally occurring steroidal saponin, has been confirmed to possess potent
anticancer properties. In the current work, two series of novel diosgenin derivatives bearing …

This work reports a graphene oxide-based nanovehicle with conjugation of pegylated folate
for targeted delivery of anticancer drugs and fluorescein-labeled peptide for therapeutic self …

Functional group substituted 1-naphthylamines, especially N-methylated ones, play
important roles in numerous chemical and biological processes. However, these …