Evidence for sponges as sister to all other animals from partitioned phylogenomics with mixture models and recoding
AK Redmond, A McLysaght - Nature communications, 2021 - nature.com
Resolving the relationships between the major lineages in the animal tree of life is
necessary to understand the origin and evolution of key animal traits. Sponges …
necessary to understand the origin and evolution of key animal traits. Sponges …
Discovery of all three types in cartilaginous fishes enables phylogenetic resolution of the origins and evolution of interferons
AK Redmond, J Zou, CJ Secombes… - Frontiers in …, 2019 - frontiersin.org
Interferons orchestrate host antiviral responses in jawed vertebrates. They are categorized
into three classes; IFN1 and IFN3 are the primary antiviral cytokine lineages, while IFN2 …
into three classes; IFN1 and IFN3 are the primary antiviral cytokine lineages, while IFN2 …
The whale shark genome reveals patterns of vertebrate gene family evolution
Chondrichthyes (cartilaginous fishes) are fundamental for understanding vertebrate
evolution, yet their genomes are understudied. We report long-read sequencing of the whale …
evolution, yet their genomes are understudied. We report long-read sequencing of the whale …
Phylotranscriptomics suggests the jawed vertebrate ancestor could generate diverse helper and regulatory T cell subsets
Background The cartilaginous fishes diverged from other jawed vertebrates~ 450 million
years ago (mya). Despite this key evolutionary position, the only high-quality cartilaginous …
years ago (mya). Despite this key evolutionary position, the only high-quality cartilaginous …
Sharks provide evidence for a highly complex TNFSF repertoire in the jawed vertebrate ancestor
Cytokines of the TNF superfamily (TNFSF) control many immunological processes and are
implicated in the etiology of many immune disorders and diseases. Despite their obvious …
implicated in the etiology of many immune disorders and diseases. Despite their obvious …
Exploration of the Nurse Shark (Ginglymostoma cirratum) Plasma Immunoproteome Using High-Resolution LC-MS/MS
Many animals of scientific importance lack species-specific reagents (eg, monoclonal
antibodies) for in-depth studies of immune proteins. Mass spectrometry (MS)-based …
antibodies) for in-depth studies of immune proteins. Mass spectrometry (MS)-based …
[PDF][PDF] Tumor necrosis factor superfamily: Ancestral functions and remodeling in early vertebrate evolution
I Marín - Genome Biology and Evolution, 2020 - academic.oup.com
The evolution of the tumor necrosis factor superfamily (TNFSF) in early vertebrates is
inferred by comparing the TNFSF genes found in humans and nine fishes: three agnathans …
inferred by comparing the TNFSF genes found in humans and nine fishes: three agnathans …
Evolutionary history of the T cell receptor complex as revealed by small-spotted catshark (Scyliorhinus canicula)
R Pettinello, AK Redmond, CJ Secombes… - Developmental & …, 2017 - Elsevier
In every jawed vertebrate species studied so far, the T cell receptor (TCR) complex is
composed of two different TCR chains (α/β or γ/δ) and a number of CD3 subunits …
composed of two different TCR chains (α/β or γ/δ) and a number of CD3 subunits …
Ancient BCMA-like genes herald B cell regulation in lampreys
The TNF superfamily ligands BAFF and APRIL interact with three receptors, BAFFR, BCMA,
and TACI, to play discrete and crucial roles in regulating B cell selection and homeostasis in …
and TACI, to play discrete and crucial roles in regulating B cell selection and homeostasis in …
Chondrichthyes: The immune system of cartilaginous fishes
H Dooley - Advances in comparative immunology, 2018 - Springer
The cartilaginous fishes (sharks, skates, rays, and chimaeras) hold a key evolutionary
position, being the most distant group to mammals that possesses a “mammalian-like” …
position, being the most distant group to mammals that possesses a “mammalian-like” …