Docosahexaenoic acid (DHA) is the predominant omega-3 (n-3) polyunsaturated fatty acid
(PUFA) found in the brain and can affect neurological function by modulating signal …

A large body of evidence supports the cardioprotective effects of the long-chain omega-3
polyunsaturated fatty acids (PUFAs), eicosapentaenoic acid (EPA), and docosahexaenoic …

Essential polyunsaturated fatty acids (PUFAs) have profound effects on brain development
and function. Abnormalities of PUFA status have been implicated in neuropsychiatric …

Background and aims The independent effects of eicosapentaenoic acid (EPA) and
docosahexaenoic acid (DHA) on chronic inflammation through their downstream lipid …

Alzheimer's disease (AD) is generally associated with lower omega-3 fatty acid intake from
fish but despite numerous studies, it is still unclear whether there are differences in omega-3 …

Epidemiological studies on Greenland Inuits in the 1970s and subsequent human studies
have established an inverse relationship between the ingestion of omega-3 fatty acids [C 20 …

Humans evolved a uniquely large brain among terrestrial mammals. Brain and nervous
tissue is rich in the omega-3 polyunsaturated fatty acid (PUFA) docosahexaenoic acid …

Fatty acid regulation of hepatic gene transcription was first reported in the early 1990s.
Several transcription factors have been identified as targets of fatty acid regulation. This …

Obese and type 2 diabetic (T2DM) patients have a high prevalence of nonalcoholic fatty liver
disease (NAFLD). NAFLD is a continuum of chronic liver diseases ranging from benign …

Long-chain polyunsaturated fatty acids (LCPUFAs) are of nutritional interest because they
are crucial for normal development of the central nervous system and have potential long …