Docosahexaenoic acid and cognition throughout the lifespan

MJ Weiser, CM Butt, MH Mohajeri - Nutrients, 2016 - mdpi.com
Docosahexaenoic acid (DHA) is the predominant omega-3 (n-3) polyunsaturated fatty acid
(PUFA) found in the brain and can affect neurological function by modulating signal …

The differential effects of eicosapentaenoic acid and docosahexaenoic acid on cardiometabolic risk factors: a systematic review

JK Innes, PC Calder - International journal of molecular sciences, 2018 - mdpi.com
A large body of evidence supports the cardioprotective effects of the long-chain omega-3
polyunsaturated fatty acids (PUFAs), eicosapentaenoic acid (EPA), and docosahexaenoic …

Pathways of polyunsaturated fatty acid utilization: implications for brain function in neuropsychiatric health and disease

JJ Liu, P Green, JJ Mann, SI Rapoport, ME Sublette - Brain research, 2015 - Elsevier
Essential polyunsaturated fatty acids (PUFAs) have profound effects on brain development
and function. Abnormalities of PUFA status have been implicated in neuropsychiatric …

EPA and DHA differentially modulate monocyte inflammatory response in subjects with chronic inflammation in part via plasma specialized pro-resolving lipid …

J So, D Wu, AH Lichtenstein, AK Tai, NR Matthan… - Atherosclerosis, 2021 - Elsevier
Background and aims The independent effects of eicosapentaenoic acid (EPA) and
docosahexaenoic acid (DHA) on chronic inflammation through their downstream lipid …

Plasma and brain fatty acid profiles in mild cognitive impairment and Alzheimer's disease

SC Cunnane, JA Schneider, C Tangney… - Journal of …, 2012 - content.iospress.com
Alzheimer's disease (AD) is generally associated with lower omega-3 fatty acid intake from
fish but despite numerous studies, it is still unclear whether there are differences in omega-3 …

Omega-3 fatty acid supplementation and cardiovascular disease: thematic review series: new lipid and lipoprotein targets for the treatment of cardiometabolic …

DB Jump, CM Depner, S Tripathy - Journal of lipid research, 2012 - ASBMB
Epidemiological studies on Greenland Inuits in the 1970s and subsequent human studies
have established an inverse relationship between the ingestion of omega-3 fatty acids [C 20 …

Docosahexaenoic acid and human brain development: evidence that a dietary supply is needed for optimal development

JT Brenna, SE Carlson - Journal of human evolution, 2014 - Elsevier
Humans evolved a uniquely large brain among terrestrial mammals. Brain and nervous
tissue is rich in the omega-3 polyunsaturated fatty acid (PUFA) docosahexaenoic acid …

Fatty acid–regulated transcription factors in the liver

DB Jump, S Tripathy, CM Depner - Annual review of nutrition, 2013 - annualreviews.org
Fatty acid regulation of hepatic gene transcription was first reported in the early 1990s.
Several transcription factors have been identified as targets of fatty acid regulation. This …

Omega-3 polyunsaturated fatty acids as a treatment strategy for nonalcoholic fatty liver disease

DB Jump, KA Lytle, CM Depner, S Tripathy - Pharmacology & therapeutics, 2018 - Elsevier
Obese and type 2 diabetic (T2DM) patients have a high prevalence of nonalcoholic fatty liver
disease (NAFLD). NAFLD is a continuum of chronic liver diseases ranging from benign …

Lipid needs of preterm infants: updated recommendations

A Lapillonne, S Groh-Wargo, CHL Gonzalez… - The Journal of …, 2013 - Elsevier
Long-chain polyunsaturated fatty acids (LCPUFAs) are of nutritional interest because they
are crucial for normal development of the central nervous system and have potential long …