Tumorigenic cells are similar to neural stem cells or embryonic neural cells in regulatory
networks, tumorigenicity and pluripotent differentiation potential. By integrating the evidence …

Flaviviruses are a genus of mostly arthropod-borne RNA viruses that cause a range of
pathologies in humans. Basic knowledge on flaviviruses is rapidly expanding, partly due to …

In order to eliminate viral infections, hundreds of interferon-stimulated genes (ISGs) are
induced via type I interferons (IFNs). However, the functions and mechanisms of most ISGs …

The tripartite motif (TRIM) protein family has been investigated in multiple human cancers,
including gastric cancer (GC). However, the role of TRIM69 in the anoikis resistance and …

Ultraviolet B (UVB) irradiation can induce reactive oxygen species (ROS) production and
apoptosis in human lens epithelial cells (HLECs), thus leading to the formation of cataracts …

Topological network alignment aims to align two networks node-wise in order to maximize
the observed common connection (edge) topology between them. The topological alignment …

In Huntington disease (HD) subtle symptoms in patients may occur years or even decades
prior to diagnosis. HD changes at a molecular level may begin as early as in cells that are …

t (1; 19)(q23; p13) is one of the most common translocation genes in childhood acute
lymphoblastic leukemia (ALL) and is also present in acute myeloid leukemia (AML) and …

In the vertebrate retina, an interplay between retinal ganglion cells (RGCs), amacrine (AC),
and bipolar (BP) cells establishes a synaptic layer called the inner plexiform layer (IPL). This …

Background c-Jun is a key regulator of gene expression. Through the formation of homo-or
heterodimers, c-JUN binds to DNA and regulates gene transcription. While c-Jun plays a …