Direct oral anticoagulants versus warfarin for preventing stroke and systemic embolic events among atrial fibrillation patients with chronic kidney disease

M Kimachi, TA Furukawa, K Kimachi… - Cochrane Database …, 2017 - cochranelibrary.com
Background Chronic kidney disease (CKD) is an independent risk factor for atrial fibrillation
(AF), which is more prevalent among CKD patients than the general population. AF causes …

[HTML][HTML] Cerebral microbleeds: a review of clinical, genetic, and neuroimaging associations

PA Yates, VL Villemagne, KA Ellis… - Frontiers in …, 2014 - frontiersin.org
Cerebral microbleeds (microbleeds) are small, punctuate hypointense lesions seen in T2*
Gradient-Recall Echo (GRE) and Susceptibility-Weighted (SWI) Magnetic Resonance …

Antithrombotic therapy for atrial fibrillation: CHEST guideline and expert panel report

GYH Lip, A Banerjee, G Boriani, C en Chiang, R Fargo… - Chest, 2018 - Elsevier
Background The risk of stroke is heterogeneous across different groups of patients with atrial
fibrillation (AF), being dependent on the presence of various stroke risk factors. We provide …

Comparison of the efficacy and safety of new oral anticoagulants with warfarin in patients with atrial fibrillation: a meta-analysis of randomised trials

CT Ruff, RP Giugliano, E Braunwald, EB Hoffman… - The Lancet, 2014 - thelancet.com
Background Four new oral anticoagulants compare favourably with warfarin for stroke
prevention in patients with atrial fibrillation; however, the balance between efficacy and …

Efficacy and safety of apixaban compared with warfarin according to age for stroke prevention in atrial fibrillation: observations from the ARISTOTLE trial

S Halvorsen, D Atar, H Yang… - European heart …, 2014 - academic.oup.com
Aims The risk of stroke in patients with atrial fibrillation (AF) increases with age. In the
ARISTOTLE trial, apixaban when compared with warfarin reduced the rate of stroke, death …

[HTML][HTML] The Significance of drug—Drug and drug—Food interactions of oral anticoagulation

P Vranckx, M Valgimigli… - … & electrophysiology review, 2018 - ncbi.nlm.nih.gov
Vitamin K antagonists (VKAs) such as warfarin are the most commonly prescribed oral
anticoagulants worldwide. However, factors affecting the pharmacokinetics of VKAs, such as …

Cost-effectiveness of mass screening for untreated atrial fibrillation using intermittent ECG recording

M Aronsson, E Svennberg, M Rosenqvist… - Ep …, 2015 - academic.oup.com
Aims The aim of this study was to estimate the cost-effectiveness of 2 weeks of intermittent
screening for asymptomatic atrial fibrillation (AF) in 75/76-year-old individuals. Methods and …

Clinical outcomes and management associated with major bleeding in patients with atrial fibrillation treated with apixaban or warfarin: insights from the ARISTOTLE …

C Held, EM Hylek, JH Alexander, M Hanna… - European heart …, 2015 - academic.oup.com
Abstract Aim In the Apixaban for Reduction in Stroke and Other Thromboembolic Events in
Atrial Fibrillation (ARISTOTLE) trial, apixaban compared with warfarin reduced the risk of …

Safety and efficacy of well managed warfarin

V Sjögren, B Grzymala-Lubanski… - Thrombosis and …, 2015 - thieme-connect.com
The safety and efficacy of warfarin in a large, unselected cohort of warfarin-treated patients
with high quality of care is comparable to that reported for non-vitamin K antagonists …

Clinical effectiveness of direct oral anticoagulants vs warfarin in older patients with atrial fibrillation and ischemic stroke: findings from the patient-centered research …

Y Xian, H Xu, EC O'Brien, S Shah, L Thomas… - JAMA …, 2019 - jamanetwork.com
Importance Current guidelines recommend direct oral anticoagulants (DOACs) over warfarin
for stroke prevention in patients with atrial fibrillation (AF) who are at high risk. Despite …