The endothelium, a monolayer of endothelial cells, constitutes the inner cellular lining of the
blood vessels (arteries, veins and capillaries) and the lymphatic system, and therefore is in …

While gap junctions support the exchange of a number of molecules between neighboring
cells, connexin hemichannels provide communication between the cytosol and the …

Cxs (connexins), the protein subunits forming gap junction intercellular communication
channels, are transported to the plasma membrane after oligomerizing into hexameric …

Gap junctions (GJ) and hemichannels (HC) formed from the protein subunits called
connexins are transmembrane conduits for the exchange of small molecules and ions …

Although the chemical nature of endothelium-derived hyperpolarizing factor (EDHF) remains
elusive, electrophysiological evidence exists for electrical communication between smooth …

Bone development and remodeling depend on complex interactions between bone-forming
osteoblasts and other cells present within the bone microenvironment, particularly vascular …

The nature of the vasodilator endothelium-derived hyperpolarizing factor (EDHF) is
controversial, putatively involving diffusible factors and/or electrotonic spread of …

An endothelium‐derived hyperpolarizing factor (EDHF) that is distinct from nitric oxide (NO)
and prostanoids has been widely hypothesized to hyperpolarize and relax vascular smooth …

Intercellular co-operation is a fundamental and widespread feature in tissues and organs.
An important mechanism ensuring multicellular homoeostasis involves signalling between …

Vertebrate cells that express connexins likely express connexin hemichannels (Cx HCs) at
their surface. In diverse cell types, surface Cx HCs can open to serve as a diffusional …