The microbiome plays an important role in a wide variety of skin disorders. Not only is the
skin microbiome altered, but also surprisingly many skin diseases are accompanied by an …

Diabetic foot ulcer (DFU) is a combination of neuropathy and various degrees of peripheral
vasculopathy in diabetic patients resulting in lower extremity infection, ulcer formation, and …

Diabetic foot ulcers (DFUs) are a life-threatening disease that often result in lower limb
amputations and a shortened lifespan. However, molecular mechanisms contributing to the …

The skin microbiota is intimately coupled with cutaneous health and disease. Interactions
between commensal microbiota and the multiple cell types involved in cutaneous wound …

Human skin functions as a physical, chemical, and immune barrier against the external
environment while also providing a protective niche for its resident microbiota, known as the …

An extreme chronic wound tissue microenvironment causes epigenetic gene silencing. An
unbiased whole-genome methylome was studied in the wound-edge tissue of patients with …

Impaired wound healing associated with recurrent Staphylococcus aureus infection and
unresolved inflammation are hallmarks of nonhealing diabetic foot ulcers (DFUs). Perforin-2 …

Diabetic wound is one of the complications of diabetes and is not easy to heal. It often
evolves into chronic ulcers, and severe patients will face amputation. Compared with normal …

MicroRNAs (miRNAs) are conserved, short, non-coding RNAs that play a crucial role in the
post-transcriptional regulation of gene expression. They have been implicated in the …

Venous leg ulcers, diabetic foot ulcers, and pressure ulcers are complex chronic wounds
with multifactorial etiologies that are associated with high patient morbidity and mortality …