Nanoparticles are often engineered as a scaffolding system to combine targeting, imaging
and/or therapeutic moieties into a unitary agent. However, mostly overlooked, the …

The design of nanoparticles is critical for their efficient use in many applications ranging from
biomedicine to sensing and energy. While shape and size are responsible for the properties …

For successful translation of targeting nanomedicines from bench to bedside, it is vital to
address their most common drawbacks namely rapid clearance and off-target accumulation …

In contact with biological fluids diverse type of biomolecules (eg, proteins) adsorb onto
nanoparticles forming protein corona. Surface properties of the coated nanoparticles, in …

Nanoparticle structural parameters, such as size, surface chemistry, and shape, are well-
recognized parameters that affect biological activities of nanoparticles. However, whether …

Highlights•Direct versus indirect analysis of the protein corona.•In situ measurements of
protein corona versus measurements requiring purification.•Characterization apart from …

Nanoparticles (NPs) represent one of the most promising tools for drug‐targeting and drug‐
delivery. However, a deeper understanding of the complex dynamics that happen after their …

Nanoparticle (NP) exposure to biological fluids in the body results in protein binding to the
NP surface, which forms a protein coating that is called the “protein corona”. To simplify …

Abstract Silica nanoparticles (SiO 2-NPs) has been extensively exploited in biomedical
fields and mostly designed to enter the circulatory system, however, few studies focused on …

Nanoparticles exposed to biological fluids such as blood, quickly interact with their
surrounding milieu resulting in a biological coating that results in large part as a function of …