Microbiome and human health: current understanding, engineering, and enabling technologies
The human microbiome is composed of a collection of dynamic microbial communities that
inhabit various anatomical locations in the body. Accordingly, the coevolution of the …
inhabit various anatomical locations in the body. Accordingly, the coevolution of the …
How vascular smooth muscle cell phenotype switching contributes to vascular disease
G Cao, X Xuan, J Hu, R Zhang, H Jin… - Cell Communication and …, 2022 - Springer
Vascular smooth muscle cells (VSMCs) are the most abundant cell in vessels. Earlier
experiments have found that VSMCs possess high plasticity. Vascular injury stimulates …
experiments have found that VSMCs possess high plasticity. Vascular injury stimulates …
Proliferation tracing reveals regional hepatocyte generation in liver homeostasis and repair
L He, W Pu, X Liu, Z Zhang, M Han, YI Li, X Huang… - Science, 2021 - science.org
INTRODUCTION Cell proliferation is a fundamental process in all multicellular organisms
that is required to enable development, tissue homeostasis, tissue repair, and tissue …
that is required to enable development, tissue homeostasis, tissue repair, and tissue …
[HTML][HTML] Tracing the skeletal progenitor transition during postnatal bone formation
Multiple distinct types of skeletal progenitors have been shown to contribute to
endochondral bone development and maintenance. However, the division of labor and …
endochondral bone development and maintenance. However, the division of labor and …
Hepatic soluble epoxide hydrolase activity regulates cerebral Aβ metabolism and the pathogenesis of Alzheimer's disease in mice
Y Wu, JH Dong, YF Dai, MZ Zhu, MY Wang, Y Zhang… - Neuron, 2023 - cell.com
Alzheimer's disease (AD) is caused by a complex interaction between genetic and
environmental factors. However, how the role of peripheral organ changes in response to …
environmental factors. However, how the role of peripheral organ changes in response to …
[HTML][HTML] Stem cells and the differentiation hierarchy in mammary gland development
NY Fu, E Nolan, GJ Lindeman… - Physiological …, 2020 - journals.physiology.org
The mammary gland is a highly dynamic organ that undergoes profound changes within its
epithelium during puberty and the reproductive cycle. These changes are fueled by …
epithelium during puberty and the reproductive cycle. These changes are fueled by …
Smooth muscle cell phenotypic diversity: At the crossroads of lineage tracing and single-cell transcriptomics
M Liu, D Gomez - Arteriosclerosis, thrombosis, and vascular …, 2019 - Am Heart Assoc
Vascular smooth muscle cells (SMC) play a critical role in controlling blood pressure and
blood distribution, as well as maintaining the structural integrity of the blood vessel. SMC …
blood distribution, as well as maintaining the structural integrity of the blood vessel. SMC …
Dual genetic tracing reveals a unique fibroblast subpopulation modulating cardiac fibrosis
M Han, Z Liu, L Liu, X Huang, H Wang, W Pu, E Wang… - Nature Genetics, 2023 - nature.com
After severe heart injury, fibroblasts are activated and proliferate excessively to form
scarring, leading to decreased cardiac function and eventually heart failure. It is unknown …
scarring, leading to decreased cardiac function and eventually heart failure. It is unknown …
Meteorin-like promotes heart repair through endothelial KIT receptor tyrosine kinase
MR Reboll, S Klede, MH Taft, CL Cai, LJ Field… - Science, 2022 - science.org
Effective tissue repair after myocardial infarction entails a vigorous angiogenic response,
guided by incompletely defined immune cell–endothelial cell interactions. We identify the …
guided by incompletely defined immune cell–endothelial cell interactions. We identify the …
Lung regeneration by multipotent stem cells residing at the bronchioalveolar-duct junction
Characterizing the stem cells responsible for lung repair and regeneration is important for
the treatment of pulmonary diseases. Recently, a unique cell population located at the …
the treatment of pulmonary diseases. Recently, a unique cell population located at the …