Sepsis is a life-threatening condition and a global disease burden. Today, the
heterogeneous syndrome is defined as severe organ dysfunction caused by a dysregulated …

Inflammatory lung diseases represent a persistent burden for patients and the global
healthcare system. The combination of high morbidity,(partially) high mortality and limited …

Sepsis-induced cardiac dysfunction can lead to death in sepsis. In this case, we targeted to
explore in detail the relative mechanism of microRNA (miR)-124-3p in sepsis-induced …

Sepsis is a heterogeneous disease with variable clinical course and several clinical
phenotypes. As it is associated with an increased risk of death, patients with this condition …

Polyclonal Intravenous Immunoglobulins (IvIg) are often administered to critically ill patients
more as an act of faith than on the basis of relevant clinical studies. This particularly applies …

Objectives Intravenous immunoglobulin (IVIG) is commonly used to treat severe COVID-19,
although the clinical outcome of such treatment remains unclear. This study evaluated the …

Background A profound inflammation-mediated lung injury with long-term acute respiratory
distress and high mortality is one of the major complications of critical COVID-19 …

Background Sepsis is a major cause of mortality and morbidity globally, with around one-
quarter of all sepsis-related deaths occurring in children under the age of 5. We conducted a …

Sepsis is a heterogeneous condition defined as life-threatening organ dysfunction caused
by a dysregulated host response to infection. For some, sepsis presents as a predominantly …

Recipients transplanted for bronchiectasis in the context of a primary immune deficiency,
such as common variable immunodeficiency, are at a high risk of severe infection in post …