Laboratory diagnosis of melioidosis: past, present and future

SKP Lau, S Sridhar, CC Ho, WN Chow… - Experimental …, 2015 - journals.sagepub.com
Melioidosis is an emerging, potentially fatal disease caused by Burkholderia pseudomallei,
which requires prolonged antibiotic treatment to prevent disease relapse. However …

Environmental Factors Associated With Soil Prevalence of the Melioidosis Pathogen Burkholderia pseudomallei: A Longitudinal Seasonal Study From South West …

T Shaw, K Assig, C Tellapragada, GE Wagner… - Frontiers in …, 2022 - frontiersin.org
Melioidosis is a seasonal infectious disease in tropical and subtropical areas caused by the
soil bacterium Burkholderia pseudomallei. In many parts of the world, including South West …

Probable airborne transmission of Burkholderia pseudomallei causing an urban outbreak of melioidosis during typhoon season in Hong Kong, China

WG Wu, MHH Shum, ITF Wong, KK Lu… - Emerging Microbes & …, 2023 - Taylor & Francis
ABSTRACT Between January 2015 and October 2022, 38 patients with culture-confirmed
melioidosis were identified in the Kowloon West (KW) Region, Hong Kong. Notably, 30 of …

Melioidosis in Hong Kong

G Lui, A Tam, EYK Tso, AKL Wu, J Zee… - Tropical Medicine and …, 2018 - mdpi.com
Melioidosis, although endemic in many parts of Southeast Asia, has not been systematically
studied in Hong Kong, which is a predominantly urban area located in the subtropics. This …

Evaluation of the Bruker Biotyper matrix-assisted laser desorption/ionization time-of-flight mass spectrometry system for identification of clinical and environmental …

H Wang, YL Chen, SH Teng, ZP Xu, YC Xu… - Frontiers in …, 2016 - frontiersin.org
Burkholderia pseudomallei is not represented in the current version of Bruker Biotyper
matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) …

Gene amplification and sequencing for bacterial identification

SKP Lau, JLL Teng, CC Ho, PCY Woo - Methods in microbiology, 2015 - Elsevier
The most important task of the clinical microbiology laboratory is to accurately identify the
responsible pathogens to species level. Phenotypic methods for bacterial identification are …

Workflow for identification of Burkholderia pseudomallei clinical isolates in Myanmar

NM Aung, KK Su, N Chantratita… - Japanese Journal of …, 2023 - jstage.jst.go.jp
Burkholderia pseudomallei, the highly infectious and causative organism of melioidosis, was
first identified in Myanmar in 1911. B. pseudomallei was identified in Myanmar because of its …

Genome-wide transposon mutagenesis analysis of Burkholderia pseudomallei reveals essential genes for in vitro and in vivo survival

YC Wong, R Naeem, M Abd El Ghany… - Frontiers in cellular …, 2022 - frontiersin.org
Introduction Burkholderia pseudomallei, a soil-dwelling microbe that infects humans and
animals is the cause of the fatal disease melioidosis. The molecular mechanisms that …

Metabolomic profiling of plasma from melioidosis patients using UHPLC-QTOF MS reveals novel biomarkers for diagnosis

SKP Lau, KC Lee, GCS Lo, VSY Ding… - International Journal of …, 2016 - mdpi.com
To identify potential biomarkers for improving diagnosis of melioidosis, we compared
plasma metabolome profiles of melioidosis patients compared to patients with other …

The melioidosis agent Burkholderia pseudomallei and related opportunistic pathogens detected in faecal matter of wildlife and livestock in northern Australia

ACR Höger, M Mayo, EP Price, V Theobald… - Epidemiology & …, 2016 - cambridge.org
The Darwin region in northern Australia has experienced rapid population growth in recent
years, and with it, an increased incidence of melioidosis. Previous studies in Darwin have …