Characterization of antimicrobial peptides toward the development of novel antibiotics

W Aoki, M Ueda - Pharmaceuticals, 2013 - mdpi.com
Antimicrobial agents have eradicated many infectious diseases and significantly improved
our living environment. However, abuse of antimicrobial agents has accelerated the …

Benzotriazole: An overview on its versatile biological behavior

I Briguglio, S Piras, P Corona, E Gavini… - European Journal of …, 2015 - Elsevier
Discovered in late 1960, azoles are heterocyclic compounds class which constitute the
largest group of available antifungal drugs. Particularly, the imidazole ring is the chemical …

Advances in synthesis and biological activities of benzotriazole analogues: A micro review

HB Bollikolla, SNM Boddapati… - Journal of …, 2023 - Wiley Online Library
Although the first synthesis of benzotriazole was performed in the 19th century still new
methods for their preparation have developed. In this micro review authors focus mostly on …

PubChem and CHEMBL beyond Lipinski

A Capecchi, M Awale, D Probst… - Molecular …, 2019 - Wiley Online Library
Seven million of the currently 94 million entries in the PubChem database break at least one
of the four Lipinski constraints for oral bioavailability, 183,185 of which are also found in the …

Voltammetric determination of amaranth and tartrazine with a new double-stranded copper (I) helicate-single-walled carbon nanotube modified screen printed …

N Nuñez-Dallos, MA Macías, O García-Beltrán… - Journal of …, 2018 - Elsevier
In this work, we report the synthesis of a new double-stranded copper (I) helicate (H) and its
use for the first time in a single-walled carbon nanotube-modified screen printed electrode …

Macrocyclic peptidomimetics with antimicrobial activity: synthesis, bioassay, and molecular modeling studies

MA Ibrahim, SS Panda, AA Oliferenko… - Organic & …, 2015 - pubs.rsc.org
Novel, cyclic peptidomimetics were synthesized by facile acylation reactions using
benzotriazole chemistry. Microbiological testing of the synthesized compounds revealed an …

Traceless Chemical Ligation from S-, O-, and N-Acyl Isopeptides

SS Panda, CD Hall, AA Oliferenko… - Accounts of Chemical …, 2014 - ACS Publications
Peptides are ubiquitous in nature where they play crucial roles as catalysts (enzymes), cell
membrane ion transporters, and structural elements (proteins) within biological systems. In …

Linear and cyclic amides with a thiophene backbone: ultrasound-promoted synthesis and crystal structures

TH Ngo, H Berndt, D Lentz… - The Journal of Organic …, 2012 - ACS Publications
A full synthetic study of linear and cyclic thiophene oligoamides has been carried out. The
combination of an ultrasonic technique to diminish the intramolecular backfolding of longer …

Green and catalyst-free synthesis of olsalazine analogs

MA Ibrahim, M Elagawany… - Green Chemistry Letters …, 2016 - Taylor & Francis
ABSTRACT A greener protocol for the synthesis of olsalazine analogs is reported.
Olsalazine analogs are prepared in high yields by a one-pot reaction of two molecules of …

Chromium (III) complexes bearing bis (benzotriazolyl) pyridine ligands: Synthesis, characterization and ethylene polymerization behavior

J Hurtado, N Nuñez-Dallos, S Movilla… - Journal of …, 2017 - Taylor & Francis
Abstract Reaction of benzotriazole with 2, 6-bis (bromomethyl) pyridine and 2, 6-
pyridinedicarbonyl dichloride yields the tridentate ligands 2, 6-bis (benzotriazol-1-ylmethyl) …