Arginase is a key hydrolase in the urea cycle that hydrolyses L-arginine to urea and L-
ornithine. Increasing number of studies in recent years demonstrate that two mammalian …

Arginase is a widely known enzyme of the urea cycle that catalyzes the hydrolysis of L-
arginine to L-ornithine and urea. The action of arginase goes beyond the boundaries of …

The tumor microenvironment is overwhelmingly dictated by macrophages, intimately
affiliated with tumors, exercising pivotal roles in multiple processes, including angiogenesis …

Cancer continues to be a leading cause of death worldwide, making the development of
new treatment methods crucial in the fight against it. With cancer incidence rates increasing …

Pregnancy is a complex process requiring tremendous physiological changes in the mother
in order to fulfill the needs of the growing fetus, and to give birth, expel the placenta and …

Conventional treatment methods are not effective enough to fight the rapid increase in
cancer cases. The interest is increasing in the investigation of herbal sources for the …

Arginases are key enzymes that hydrolyze L-arginine to urea and L-ornithine in the urea
cycle. The two arginase isoforms, arginase 1 (ARG1) and arginase 2 (ARG2), regulate the …

In recent years, nanotechnology has revolutionized various sectors, particularly in
nanomedicine, where nanomaterials are used for diagnosis, monitoring, control, prevention …

Cancer immunotherapy has evolved significantly over the last decade, with therapeutics
targeting the adaptive immune system showing exciting effects in clinics. Yet, the modulation …

Short-term hypoxic states can influence the health and life activities of lowlanders who travel
shortly to high altitudes, in transitory situations, such as surgical ischemia-reperfusion (to …