Curcumin is a naturally occurring polyphenolic compound present in rhizome of Curcuma
longa belonging to the family zingiberaceae. Growing experimental evidence revealed that …

Memory, one of the most vital aspects of the human brain, is necessary for the effective
survival of an individual.'Memory'can be defined in various ways but in an overall view …

Background: Despite the extensive research in recent years, the current treatment modalities
for neurological disorders are suboptimal. Curcumin, a polyphenol majorly found in …

The pilocarpine animal model of status epilepticus is a well-established, clinically
translatable model that satisfies all of the criteria essential for an animal model of status …

This article describes the recent advances in epileptogenesis and novel therapeutic
approaches for the prevention of epilepsy, with a special emphasis on the pharmacological …

Despite several beneficial effects of curcumin, its medical application has been hampered
due to low water solubility. To improve the aqueous solubility of curcumin, it has been …

Traditionally, selected plant sources have been explored for medicines to treat convulsions.
This continues today, especially in countries with low-income rates and poor medical …

Mitochondria are both a primary source of reactive oxygen species (ROS) and a sensitive
target of oxidative stress; damage to mitochondria can result in bioenergetic dysfunction and …

Lithium is abundantly administered against bipolar disorder. On the other hand, the lithium-
induced renal injury is a clinical complication which commonly reveals as drug-induced …

Currently available antiepileptic drugs (AEDs) fail to control seizures in 30% of patients.
Genomics-based drug repurposing (GBR) offers the potential of savings in the time and cost …