MicroRNAs: from mechanism to organism
PJ Dexheimer, L Cochella - Frontiers in cell and developmental …, 2020 - frontiersin.org
MicroRNAs (miRNAs) are short, regulatory RNAs that act as post-transcriptional repressors
of gene expression in diverse biological contexts. The emergence of small RNA-mediated …
of gene expression in diverse biological contexts. The emergence of small RNA-mediated …
Identification and consequences of miRNA–target interactions—beyond repression of gene expression
Comparative genomics analyses and high-throughput experimental studies indicate that a
microRNA (miRNA) binds to hundreds of sites across the transcriptome. Although the …
microRNA (miRNA) binds to hundreds of sites across the transcriptome. Although the …
Zygotic genome activation during the maternal-to-zygotic transition
MT Lee, AR Bonneau, AJ Giraldez - Annual review of cell and …, 2014 - annualreviews.org
Embryogenesis depends on a highly coordinated cascade of genetically encoded events. In
animals, maternal factors contributed by the egg cytoplasm initially control development …
animals, maternal factors contributed by the egg cytoplasm initially control development …
Biogenesis and regulation of the let-7 miRNAs and their functional implications
H Lee, S Han, CS Kwon, D Lee - Protein & cell, 2016 - academic.oup.com
The let-7 miRNA was one of the first miRNAs discovered in the nematode, Caenorhabditis
elegans, and its biological functions show a high level of evolutionary conservation from the …
elegans, and its biological functions show a high level of evolutionary conservation from the …
microRNA functions
N Bushati, SM Cohen - Annu. Rev. Cell Dev. Biol., 2007 - annualreviews.org
microRNAs (miRNAs) are small noncoding RNAs that play important roles in
posttranscriptional gene regulation. In animal cells, miRNAs regulate their targets by …
posttranscriptional gene regulation. In animal cells, miRNAs regulate their targets by …
[HTML][HTML] Discrete small RNA-generating loci as master regulators of transposon activity in Drosophila
Drosophila Piwi-family proteins have been implicated in transposon control. Here, we
examine piwi-interacting RNAs (piRNAs) associated with each Drosophila Piwi protein and …
examine piwi-interacting RNAs (piRNAs) associated with each Drosophila Piwi protein and …
Regulation and function of miRNA-21 in health and disease
R Kumarswamy, I Volkmann, T Thum - RNA biology, 2011 - Taylor & Francis
The small regulatory RNA microRNA-21 (miR-21) plays a crucial role in a plethora of
biological functions and diseases including development, cancer, cardiovascular diseases …
biological functions and diseases including development, cancer, cardiovascular diseases …
Determining the role of microRNAs in psychiatric disorders
Recent studies have revealed that patients with psychiatric disorders have altered
microRNA (miRNA) expression profiles in the circulation and brain. Furthermore, animal …
microRNA (miRNA) expression profiles in the circulation and brain. Furthermore, animal …
Codon usage and 3′ UTR length determine maternal mRNA stability in zebrafish
The control of mRNA stability plays a central role in regulating gene expression. In
metazoans, the earliest stages of development are driven by maternally supplied mRNAs …
metazoans, the earliest stages of development are driven by maternally supplied mRNAs …
A novel class of small RNAs bind to MILI protein in mouse testes
Abstract Small RNAs bound to Argonaute proteins recognize partially or fully complementary
nucleic acid targets in diverse gene-silencing processes,,,. A subgroup of the Argonaute …
nucleic acid targets in diverse gene-silencing processes,,,. A subgroup of the Argonaute …