On the potential of micro-flow LC-MS/MS in proteomics
Introduction Due to its excellent sensitivity, nano-flow liquid chromatography tandem mass
spectrometry (LC-MS/MS) is the mainstay in proteome research; however, this comes at the …
spectrometry (LC-MS/MS) is the mainstay in proteome research; however, this comes at the …
Periodic mesoporous organosilica for chromatographic stationary phases: From synthesis strategies to applications
B Liu, H Li, K Quan, J Chen, H Qiu - TrAC Trends in Analytical Chemistry, 2023 - Elsevier
Periodic mesoporous organosilica (PMO) materials with organic functionalities in
mesoporous frameworks have received a lot of attention in multiple fields. This particular …
mesoporous frameworks have received a lot of attention in multiple fields. This particular …
Review of recent advances in development and applications of organic‐silica hybrid monoliths
Z Zajickova - Journal of Separation Science, 2023 - Wiley Online Library
Organic‐silica hybrid monoliths attracted attention as an alternative to extensively
researched organic polymer‐based and silica‐based counterparts. The development and …
researched organic polymer‐based and silica‐based counterparts. The development and …
Chromatographic separation of peptides and proteins for characterization of proteomes
Y Liang, L Zhang, Y Zhang - Chemical Communications, 2023 - pubs.rsc.org
Characterization of proteomes aims to comprehensively characterize proteins in cells or
tissues via two main strategies:(1) bottom-up strategy based on the separation and …
tissues via two main strategies:(1) bottom-up strategy based on the separation and …
Preparation and Characterization of Nano-Fe3O4 and Its Application for C18-Functionalized Magnetic Nanomaterials Used as Chromatographic Packing Materials
WX Liu, WN Zhou, S Song, YG Zhao, Y Lu - Nanomaterials, 2023 - mdpi.com
A new type of magnetic nanomaterial with Fe3O4 as the core and organic polymer as the
shell was synthesized by seed emulsion polymerization. This material not only overcomes …
shell was synthesized by seed emulsion polymerization. This material not only overcomes …
Surface-Charged Hybrid Monolithic Column for MS-Compatible Peptide Separation with High Peak Capacity and Its Application in Proteomic Analysis
C Wang, Y Liang, X Yang, B Zhong, X Zhang… - Analytical …, 2022 - ACS Publications
For bottom-up proteomics, peptide separation with high peak capacity under MS-compatible
conditions is of vital significance to increase proteome coverage. Herein, a surface-charged …
conditions is of vital significance to increase proteome coverage. Herein, a surface-charged …
Mapping the Protein Kinome: Current Strategy and Future Direction
Z Hou, H Liu - Cells, 2023 - mdpi.com
The kinome includes over 500 different protein kinases, which form an integrated kinase
network that regulates cellular phosphorylation signals. The kinome plays a central role in …
network that regulates cellular phosphorylation signals. The kinome plays a central role in …
One-step formation of functionalized mesoporous shell on silica core for chromatography
B Liu, K Quan, J Chen, H Zhang, H Qiu - Colloids and Surfaces A …, 2024 - Elsevier
Since stationary phase is the key to chromatographic separations, it is worth pursuing
simpler and more efficient methods for preparing chromatographic stationary phases. In this …
simpler and more efficient methods for preparing chromatographic stationary phases. In this …
Strategies for mapping protein hydrolysate profiles and pharmacokinetics based on non-targeted proteomics combining skyline-aided quantitative techniques
S Mao, W Jin, S Fu, K Liu, F Xu, L Wu, Y Xu, H Yang… - Analytica Chimica …, 2023 - Elsevier
Numerous works have been focused on the bioactivities of protein hydrolysates (PHs) and
their application in food or drug formulations, but their composition and pharmacokinetics …
their application in food or drug formulations, but their composition and pharmacokinetics …
Characterization of hybrid organo‐silica monoliths for possible application in the gradient elution of peptides
A Kosmáková, Z Zajickova… - Journal of Separation …, 2023 - Wiley Online Library
We characterized thermally polymerized organo‐silica hybrid monolithic capillaries to test
their applicability in the gradient elution of peptides. We have used a single‐pot approach …
their applicability in the gradient elution of peptides. We have used a single‐pot approach …