Photoacoustic techniques have shown promise in identifying molecular changes in bone
tissue and visualizing tissue microstructure. This capability represents significant …

Abstract Objective and Impact Statement. To study the feasibility of combined functional
photoacoustic (PA) and quantitative ultrasound (US) for diagnosis of osteoporosis in vivo …

In this study, we investigated the feasibility of using photoacoustic time-frequency spectral
analysis (PA-TFSA) for evaluating the bone mineral density (BMD) and bone structure …

Significance: Orthopedic surgery currently comprises over 1.5 million cases annually in the
United States alone and is growing rapidly with aging populations. Emerging optical sensing …

Osteoporosis affects one-third of the elderly population worldwide with associated health
care costs amounting to tens of billions of dollars annually. Identifying and treating the …

Few reports quantitatively compare the performance of photoacoustic tomography (PAT)
versus fluorescence molecular tomography (FMT) in vivo. We compared both modalities for …

Long cortical bone allows axial transmission of ultrasonic guided waves, which has been
utilized for osteoporosis evaluation. Benefiting structural and molecular sensitivity …

In this chapter, recent piezoelectric and opto-acoustic studies on bone are introduced. The
former are certainly related to ultrasound since piezoelectricity is one of the electro …

Photoacoustic (PA) technique involving both ultrasound and light has been explored for
potential application in the assessment of bone health. The optical and ultrasound …

Osteoporosis is a bone disease with large impact on quality of life that requires early
diagnosis for best clinical outcome. Photoacoustics (PA) is an emerging modality that …