Diabetic peripheral neuropathy (DPN) is the most common complication of diabetes, with
several underlying pathophysiological mechanisms, some of which are still uncertain. The …

Dry eye can be caused by a variety of iatrogenic interventions. The increasing number of
patients looking for eye care or cosmetic procedures involving the eyes, together with a …

Corneal nerves are responsible for the sensations of touch, pain, and temperature and play
an important role in the blink reflex, wound healing, and tear production and secretion …

The cornea is one of the most densely innervated and sensitive tissues in the body. In
addition to their important sensory functions, corneal nerves induce reflex tear production …

In the cornea, resident immune cells are in close proximity to sensory nerves, consistent with
their important roles in the maintenance of nerves in both homeostasis and inflammation …

The cornea is the most densely innervated and sensitive tissue in the body. The cornea is
exclusively innervated by C-and A-delta fibers, including mechano-nociceptors that are …

Purpose: To investigate the entire nerve architecture and content of the two main sensory
neuropeptides in mouse cornea to determine if it is a good model with similarities to human …

The eye is innervated by neurons derived from both the central nervous system and
peripheral nervous system (PNS). While much is known about retinal neurobiology and …

Purpose.: We determined whether nucleases are deficient in the tear fluid of dry eye disease
(DED) patients, and whether this causes extracellular DNA (eDNA) and neutrophil …

Purpose: To explore the neurotrophic factor expression in corneal epithelium and evaluate
their effects on the trigeminal ganglion (TG) neurite outgrowth and corneal nerve …