Stem cell‐based dental pulp regeneration: insights from signaling pathways

C Liang, L Liao, W Tian - Stem cell reviews and reports, 2021 - Springer
Deep caries, trauma, and severe periodontitis result in pulpitis, pulp necrosis, and eventually
pulp loss. However, no clinical therapy can regenerate lost pulp. A novel pulp regeneration …

Glutamine addiction and therapeutic strategies in lung cancer

K Vanhove, E Derveaux, GJ Graulus… - International journal of …, 2019 - mdpi.com
Lung cancer cells are well-documented to rewire their metabolism and energy production
networks to support rapid survival and proliferation. This metabolic reorganization has been …

Role of glutamine and interlinked asparagine metabolism in vessel formation

H Huang, S Vandekeere, J Kalucka, L Bierhansl… - The EMBO …, 2017 - embopress.org
Endothelial cell (EC) metabolism is emerging as a regulator of angiogenesis, but the precise
role of glutamine metabolism in EC s is unknown. Here, we show that depriving EC s of …

Role of glutamine and its metabolite ammonia in crosstalk of cancer-associated fibroblasts and cancer cells

X Li, H Zhu, W Sun, X Yang, Q Nie, X Fang - Cancer cell international, 2021 - Springer
Abstract Cancer-associated fibroblasts (CAFs), the most abundant cells in the tumor
microenvironment, play an indispensable role in cancer initiation, progression, metastasis …

Glutamine promotes ovarian cancer cell proliferation through the mTOR/S6 pathway

L Yuan, X Sheng, AK Willson… - Endocrine-related …, 2015 - erc.bioscientifica.com
Glutamine is one of the main nutrients used by tumor cells for biosynthesis. Therefore,
targeted inhibition of glutamine metabolism may have anti-tumorigenic implications. In the …

lncRNA DANCR suppresses odontoblast-like differentiation of human dental pulp cells by inhibiting wnt/β-catenin pathway

L Chen, Z Song, S Huang, R Wang, W Qin, J Guo… - Cell and tissue …, 2016 - Springer
Long noncoding RNAs (lncRNAs) have recently emerged as an important class of regulatory
molecules in diverse biological processes, although lncRNA involvement in the odontoblast …

Glutamine metabolism and its effects on immune response: molecular mechanism and gene expression

DC de Oliveira, F da Silva Lima, T Sartori, ACA Santos… - Nutrire, 2016 - Springer
This article aims to review glutamine metabolism and its effects on the immune response.
Selected topics are addressed, particularly the effect of glutamine on cell survival and …

Magnetic nanocomposite scaffold-induced stimulation of migration and odontogenesis of human dental pulp cells through integrin signaling pathways

HM Yun, ES Lee, M Kim, JJ Kim, JH Lee, HH Lee… - PLoS …, 2015 - journals.plos.org
Magnetism is an intriguing physical cue that can alter the behaviors of a broad range of
cells. Nanocomposite scaffolds that exhibit magnetic properties are thus considered useful …

Metabolic signatures of distinct endothelial phenotypes

SJ Dumas, M García-Caballero, P Carmeliet - Trends in Endocrinology & …, 2020 - cell.com
Angiogenesis is crucial for the development of the blood vasculature during embryogenesis,
but also contributes to cancer and other diseases. While therapeutic targeting of endothelial …

Odontoblastic differentiation, inflammatory response, and angiogenic potential of 4 calcium silicate–based cements: Micromega MTA, ProRoot MTA, RetroMTA, and …

SW Chang, WJ Bae, JK Yi, S Lee, DW Lee, KY Kum… - Journal of …, 2015 - Elsevier
Introduction The aim of this study was to analyze the effects of different calcium silicate–
based cements (CSCs) for pulp capping materials including MicroMega MTA (MMTA; …