Explosive cell lysis as a mechanism for the biogenesis of bacterial membrane vesicles and biofilms
L Turnbull, M Toyofuku, AL Hynen, M Kurosawa… - Nature …, 2016 - nature.com
Many bacteria produce extracellular and surface-associated components such as
membrane vesicles (MVs), extracellular DNA and moonlighting cytosolic proteins for which …
membrane vesicles (MVs), extracellular DNA and moonlighting cytosolic proteins for which …
Clonal expansion under the microscope: studying lymphocyte activation and differentiation using live‐cell imaging
M Polonsky, B Chain… - Immunology and cell …, 2016 - Wiley Online Library
Clonal expansion of lymphocytes is a hallmark of vertebrate adaptive immunity. A small
number of precursor cells that recognize a specific antigen proliferate into expanded clones …
number of precursor cells that recognize a specific antigen proliferate into expanded clones …
Polarized cells, polarized views: asymmetric cell division in hematopoietic cells
K Pham, F Sacirbegovic, SM Russell - Frontiers in immunology, 2014 - frontiersin.org
It has long been recognized that alterations in cell shape and polarity play important roles in
coordinating lymphocyte functions. In the last decade, a new aspect of lymphocyte polarity …
coordinating lymphocyte functions. In the last decade, a new aspect of lymphocyte polarity …
Black silicon: substrate for laser 3D micro/nano-polymerization
A Žukauskas, M Malinauskas, A Kadys… - Optics express, 2013 - opg.optica.org
We demonstrate that black silicon (b-Si) made by dry plasma etching is a promising
substrate for laser three-dimensional (3D) micro/nano-polymerization. High aspect ratio Si …
substrate for laser three-dimensional (3D) micro/nano-polymerization. High aspect ratio Si …
Automated profiling of individual cell–cell interactions from high-throughput time-lapse imaging microscopy in nanowell grids (TIMING)
Motivation: There is a need for effective automated methods for profiling dynamic cell–cell
interactions with single-cell resolution from high-throughput time-lapse imaging data …
interactions with single-cell resolution from high-throughput time-lapse imaging data …
Developing T cells form an immunological synapse for passage through the β-selection checkpoint
The β-selection checkpoint of T cell development tests whether the cell has recombined its
genomic DNA to produce a functional T cell receptor β (TCRβ). Passage through the β …
genomic DNA to produce a functional T cell receptor β (TCRβ). Passage through the β …
Asymmetric cell division during T cell development controls downstream fate
K Pham, R Shimoni, M Charnley… - Journal of Cell …, 2015 - rupress.org
During mammalian T cell development, the requirement for expansion of many individual T
cell clones, rather than merely expansion of the entire T cell population, suggests a possible …
cell clones, rather than merely expansion of the entire T cell population, suggests a possible …
The functional contribution of calcium ion flux heterogeneity in T cells
SN Christo, KR Diener… - Immunology and cell …, 2015 - Wiley Online Library
The role of intracellular calcium ion oscillations in T‐cell physiology is being increasingly
appreciated by studies that describe how unique temporal and spatial calcium ion …
appreciated by studies that describe how unique temporal and spatial calcium ion …
A new role for Notch in the control of polarity and asymmetric cell division of developing T cells
M Charnley, M Ludford-Menting… - Journal of Cell …, 2020 - journals.biologists.com
ABSTRACT A fundamental question in biology is how single cells can reliably produce
progeny of different cell types. Notch signalling frequently facilitates fate determination …
progeny of different cell types. Notch signalling frequently facilitates fate determination …
The actin‐driven spatiotemporal organization of T‐cell signaling at the system scale
T cells are activated through interaction with antigen‐presenting cells (APC s). During
activation, receptors and signaling intermediates accumulate in diverse spatiotemporal …
activation, receptors and signaling intermediates accumulate in diverse spatiotemporal …