Acute myeloid leukemia (AML) is a heterogeneous hematopoietic neoplasm which results in
clonal proliferation of abnormally differentiated hematopoietic cells. In this review …

The rare nevus sebaceous (NS) syndrome (NSS) includes cortical malformations and drug-
resistant epilepsy. Somatic RAS-pathway genetic variants are pathogenetic in NS, but not …

A better understanding of the interaction between extrinsic factors and surface receptors on
stem cells will greatly benefit stem cell research and applications. Recently, we showed that …

Oncocytic sinonasal papillomas (OSPs) are benign tumours of the sinonasal tract, a subset
of which are associated with synchronous or metachronous sinonasal squamous cell …

The Ras family genes are proto-oncogenes that are highly conserved from Drosophila to
humans. In Drosophila, Ras V12 is a constitutively activated form of the Ras oncoprotein …

Vascular endothelial growth factor-C (VEGF-C) has been implicated in epithelial-
mesenchymal transition (EMT) processes and various human cancers, including skin …

Monocyte/macrophages are important players in orchestrating the immune response as well
as connecting innate and adaptive immunity. Myelopoiesis and monopoiesis are …

Regulation of stem cells is essential for development and adult tissue homoeostasis. The
proper control of stem cell self-renewal and differentiation maintains organ physiology, and …

The Warburg effect is probably the most prominent metabolic feature of cancer cells,
although little is known about the underlying mechanisms and consequences. Here, we set …

K-Ras is a well-studied oncogene, and its mutation is frequently found in epithelial cancers
like pancreas, lung, and colorectal cancers. Cancer cells harboring K-Ras mutations are …