Molecularly stimuli-responsive self-assembled peptide nanoparticles for targeted imaging and therapy
Y Zhou, Q Li, Y Wu, X Li, Y Zhou, Z Wang, H Liang… - ACS …, 2023 - ACS Publications
Self-assembly has emerged as an extensively used method for constructing biomaterials
with sizes ranging from nanometers to micrometers. Peptides have been extensively …
with sizes ranging from nanometers to micrometers. Peptides have been extensively …
NBD-based synthetic probes for sensing small molecules and proteins: design, sensing mechanisms and biological applications
Compounds with a nitrobenzoxadiazole (NBD) skeleton exhibit prominent useful properties
including environmental sensitivity, high reactivity toward amines and biothiols (including …
including environmental sensitivity, high reactivity toward amines and biothiols (including …
Intra-Lysosomal Peptide Assembly for the High Selectivity Index against Cancer
Lysosomes remain powerful organelles and important targets for cancer therapy because
cancer cell proliferation is greatly dependent on effective lysosomal function. Recent studies …
cancer cell proliferation is greatly dependent on effective lysosomal function. Recent studies …
Synthesizing biomaterials in living organisms
X Zhang, J Wang, Y Zhang, Z Yang, J Gao… - Chemical Society …, 2023 - pubs.rsc.org
Living organisms fabricate biomacromolecules such as DNA, RNA, and proteins by the self-
assembly process. The research on the mechanism of biomacromolecule formation also …
assembly process. The research on the mechanism of biomacromolecule formation also …
A comprehensive review on peptide-bearing biomaterials: From ex situ to in situ self-assembly
SY Qin, JQ Feng, YJ Cheng, WL Liu, AQ Zhang… - Coordination Chemistry …, 2024 - Elsevier
In the last few decades, we have witnessed the great advances of molecular self-assembly
in biomedical applications. Among the building blocks for molecular self-assembly, peptide …
in biomedical applications. Among the building blocks for molecular self-assembly, peptide …
Supramolecular self‐assembly in living cells
M Dergham, S Lin, J Geng - Angewandte Chemie, 2022 - Wiley Online Library
Supramolecular interactions rely on non‐covalent forces, such as hydrophobic effects,
hydrogen‐bonding, and electrostatic interactions, which govern many intracellular biological …
hydrogen‐bonding, and electrostatic interactions, which govern many intracellular biological …
Intranuclear nanoribbons for selective killing of osteosarcoma cells
Herein, we show intranuclear nanoribbons formed upon dephosphorylation of leucine‐rich L‐
or D‐phosphopeptide catalyzed by alkaline phosphatase (ALP) to selectively kill …
or D‐phosphopeptide catalyzed by alkaline phosphatase (ALP) to selectively kill …
Enzymatically forming intranuclear peptide assemblies for selectively killing human induced pluripotent stem cells
Tumorigenic risk of undifferentiated human induced pluripotent stem cells (iPSCs), being a
major obstacle for clinical application of iPSCs, requires novel approaches for selectively …
major obstacle for clinical application of iPSCs, requires novel approaches for selectively …
Dynamic responsiveness of self‐assembling peptide‐based nano‐drug systems
Y Wang, J Zhan, J Huang, X Wang… - Interdisciplinary …, 2023 - Wiley Online Library
Dynamic‐responsive self‐assembly is the process of ordered supramolecular structure
formation or reversible decomposition from building blocks. This process is driven by non …
formation or reversible decomposition from building blocks. This process is driven by non …
Supramolecular Senolytics via Intracellular Oligomerization of Peptides in Response to Elevated Reactive Oxygen Species Levels in Aging Cells
S Kim, JB Chae, D Kim, CW Park, Y Sim… - Journal of the …, 2023 - ACS Publications
Senolytics, which eliminate senescent cells from tissues, represent an emerging therapeutic
strategy for various age-related diseases. Most senolytics target antiapoptotic proteins …
strategy for various age-related diseases. Most senolytics target antiapoptotic proteins …