Formaldehyde in brain: an overlooked player in neurodegeneration?
K Tulpule, R Dringen - Journal of Neurochemistry, 2013 - Wiley Online Library
Formaldehyde is an environmental pollutant that is also generated in substantial amounts in
the human body during normal metabolism. This aldehyde is a well‐established neurotoxin …
the human body during normal metabolism. This aldehyde is a well‐established neurotoxin …
The toxic effects of formaldehyde on the nervous system
Abstract Formaldehyde (FA)(formula: HCHO; IUPAC name: metanal) is a member of the
aldehyde family and is one of the simplest organic molecules. FA is an irritating, colorless …
aldehyde family and is one of the simplest organic molecules. FA is an irritating, colorless …
Formaldehyde and brain disorders: a meta-analysis and bioinformatics approach
While there is significant investigation and investment in brain and neurodegenerative
disease research, current understanding of the etiologies of illnesses like Alzheimer's …
disease research, current understanding of the etiologies of illnesses like Alzheimer's …
Prospective study of chemical exposures and amyotrophic lateral sclerosis
MG Weisskopf, N Morozova, EJ O'Reilly… - Journal of Neurology …, 2009 - jnnp.bmj.com
Background: Although environmental toxins, including pesticides, are suspected of
contributing to the risk of amyotrophic lateral sclerosis (ALS), no data exist from large …
contributing to the risk of amyotrophic lateral sclerosis (ALS), no data exist from large …
Hydrogen sulfide inhibits formaldehyde-induced endoplasmic reticulum stress in PC12 cells by upregulation of SIRT-1
X Li, KY Zhang, P Zhang, LX Chen, L Wang, M Xie… - PloS one, 2014 - journals.plos.org
Background Formaldehyde (FA), a well-known environmental pollutant, has been classified
as a neurotoxic molecule. Our recent data demonstrate that hydrogen sulfide (H2S), the third …
as a neurotoxic molecule. Our recent data demonstrate that hydrogen sulfide (H2S), the third …
Amyloid-like aggregates of neuronal tau induced by formaldehyde promote apoptosis of neuronal cells
CL Nie, XS Wang, Y Liu, S Perrett, RQ He - BMC neuroscience, 2007 - Springer
Background The microtubule associated protein tau is the principle component of
neurofibrillar tangles, which are a characteristic marker in the pathology of Alzheimer's …
neurofibrillar tangles, which are a characteristic marker in the pathology of Alzheimer's …
Methylprednisolone fails to improve functional and histological outcome following spinal cord injury in rats
JE Pereira, LM Costa, AM Cabrita, PA Couto… - Experimental …, 2009 - Elsevier
Currently, methylprednisolone sodium succinate (MPSS) is the standard treatment following
acute spinal cord injury (SCI) as a consequence of the results obtained from the National …
acute spinal cord injury (SCI) as a consequence of the results obtained from the National …
Rolipram promotes functional recovery after contusive thoracic spinal cord injury in rats
LM Costa, JE Pereira, VM Filipe, LG Magalhães… - Behavioural brain …, 2013 - Elsevier
Numerous animal model studies in the past decade have demonstrated that
pharmacological elevation of cyclic AMP (cAMP) alone, or in combination with other …
pharmacological elevation of cyclic AMP (cAMP) alone, or in combination with other …
Prenatal exposure to a non-steroidal anti-inflammatory drug or saline solution impairs sciatic nerve morphology: a stereological and histological study
The toxic effect of non-steroidal anti-inflammatory drugs (NSAIDs) during development has
been widely investigated. While it has been shown that these drugs impair central nervous …
been widely investigated. While it has been shown that these drugs impair central nervous …
Effects of postnatal formaldehyde exposure on pyramidal cell number, volume of cell layer in hippocampus and hemisphere in the rat: a stereological study
The purpose of the present study was to determine whether exposure of neonatal rats to
formaldehyde (FA) had either early or delayed effects on the numbers of pyramidal cells in …
formaldehyde (FA) had either early or delayed effects on the numbers of pyramidal cells in …