Background and aims By examining pertinent studies, the current review investigated the
relationship between ACE gene insertion/deletion (I/D) and the risk factors for CVD in order …

Genome-wide association studies significantly increased the number of hypertension risk
variants; however, most of them focused on European societies. There is lack of such …

Background: Essential hypertension is a complex genetic disorder influenced by diverse
environmental factors. Of the various physiological pathways affecting the homeostasis of …

Hypertension, a major risk factor for cardiovascular diseases, is among the leading causes
of morbidity and mortality worldwide. Genetic predisposition to the risk of developing …

Genetic variants of renin angiotensin system (RAS) gene play a significant role in the
pathogenesis of essential hypertension and cardiovascular diseases. In the present study …

Background The angiotensin-converting enzyme (ACE) gene in humans has an insertion-
deletion (I/D) polymorphic state in intron 16 on chromosome 17q23. This polymorphism has …

Background Although the exact cause of Alzheimer's disease is unknown, most experts
believe that it is caused by a combination of factors rather than a single cause. Age, gene …

The objective of this study was to examine the influence of ACE (I/D) genotypes on
recognized risk variables for hypertension and Metabolic Syndrome in two ethnic population …

The purpose of this study was to assess clustering of Metabolic Syndrome components in
aged Slovaks, and to investigate whether insertion/deletion (I/D) polymorphism of the human …

Epidemiological studies have demonstrated that several specific environmental factors and
candidate genes influence the human variation in blood pressure. The aim of this study was …