Background: Chronic obstructive pulmonary disease (COPD) is a leading cause of
morbidity, mortality, and resource use worldwide. The goal of this Official American Thoracic …

Radiological images have been assessed qualitatively in most clinical settings by the expert
eyes of radiologists and other clinicians. On the other hand, quantification of radiological …

Significant heterogeneity of clinical presentation and disease progression exists within
chronic obstructive pulmonary disease (COPD). Although FEV1 inadequately describes this …

Phosphorescence is a process that slowly releases the photoexcitation energy after the
removal of the excitation source. Although transition metal complexes and purely organic …

During the past several years there has been extensive development and application of
hyperpolarized helium‐3 (HP 3He) magnetic resonance imaging (MRI) in clinical respiratory …

Rationale: Low-attenuation areas assessed by computed tomography reflect the extent of
pathological emphysema and correlate with airflow limitation and mortality in patients with …

Chronic obstructive pulmonary disease (COPD) is a heterogeneous disease that is
characterized by chronic airflow limitation. Unraveling of this heterogeneity is challenging …

Chronic obstructive pulmonary disease (COPD) is a complex disease with multiple
phenotypes that cannot be identified through measurement of lung function alone. The …

Electrical impedance tomography (EIT) is a functional imaging modality capable of tracing
continuously regional pulmonary gas volume changes. The aim of our study was to …

BACKGROUND: Matrix metalloproteinase (MMP)-12 has been implicated in the
pathogenesis of both chronic obstructive pulmonary disease (COPD) and asthma. The …