Rapid development of stimuli-responsive drug delivery systems (DDSs) for tumor therapy
has raised increasing interest in recent decades, and many nanomedicines are prepared to …

Introduction There are many intra-articular hyaluronic acid (IA-HA) products on the market
that have known intrinsic differences in molecular size, source, and structure. The current …

Background Celastrol has been proven effective in anti-inflammatory but was limited in the
clinic due to the poor solubility and side effects induced by low bioavailability. Osteoarthritis …

Novel strategies have been proposed for articular cartilage damage occurring during
osteoarthritis (OA) and-among these-Extracorporeal Shock Wave Therapy (ESWT), intra …

Silicate bioceramics have been shown to possess excellent cytocompatibility and
osteogenic activity, but the exact mechanism is still unclear. Protein adsorption is the first …

Colorectal cancer is one of the crucial reasons of morbidity and mortality globally. It has
been postulated that functionally bioactive components found in certain foods may have …

The alteration of the extracellular matrix (ECM) homeostasis plays an important role in the
development of osteoarthritis (OA). The pathological changes of OA are mainly manifested …

Although several researchers have attested deleterious effects of smoking to the
musculoskeletal system, the association between smoking and the onset of osteoarthritis …

Background: The study aimed to investigate the effects of the active ingredient, nimodipine,
on chondrocyte proliferation and extracellular matrix (ECM) structures in cartilage tissue …

In the literature, there have been no studies showing clear results on how radio‐contrast
pharmaceuticals would affect intact disc tissue cells. In this context, it was aimed to evaluate …