Dementia, a prevalent condition among older individuals, has profound societal
implications. Extensive research has resulted in no cure for what is perceived as the most …

Research into Alzheimer's Disease (AD) describes a link between AD and the resident
immune cells of the brain, the microglia. Further, this suspected link is thought to have …

Background Posterior cortical atrophy is a rare syndrome characterised by early, prominent,
and progressive impairment in visuoperceptual and visuospatial processing. The disorder …

Abstract INTRODUCTION The “A/T/N”(amyloid/tau/neurodegeneration) framework provides
a biological basis for Alzheimer's disease (AD) diagnosis and can encompass additional …

Introduction Visual naming ability reflects semantic memory retrieval and is a hallmark deficit
of Alzheimer's disease (AD). Naming impairment is most prominently observed in the late …

Alzheimer's disease (AD) diagnosis utilizing single modality neuroimaging data has
limitations. Multimodal fusion of complementary biomarkers may improve diagnostic …

Objective We compared the accuracy of amyloid and [18F] Flortaucipir (FTP) tau positron
emission tomography (PET) visual reads for distinguishing patients with mild cognitive …

Brain inflammation, with an increased density of microglia and macrophages, is an important
component of Alzheimer's disease (AD) and a potential therapeutic target. However, it is …

INTRODUCTION We used sex and apolipoprotein E ε4 (APOE ε4) carrier status as
predictors of pathologic burden in early‐onset Alzheimer's disease (EOAD). METHODS We …

Introduction Posterior Cortical Atrophy (PCA) is a syndrome characterized by a progressive
decline in higher-order visuospatial processing, leading to symptoms such as space …