Glycosylation is an important posttranslational modifier of proteins and lipid conjugates
critical for the stability and function of these macromolecules. Particularly important are N …

Hepatocellular carcinoma (HCC) is a leading cause of cancer-related death worldwide, and
the cancer with the fastest increase in mortality in the United States, with more than 39,000 …

Acute phase proteins (APPs) are a group of circulating plasma proteins which undergo
changes quantitatively or qualitatively at the time of inflammation. Many of these APPs are …

Glycosylation changes are key molecular events in tumorigenesis, progression and
glycosyltransferases play a vital role in the this process. FUT8 belongs to the …

Liver cancer is the fifth most common cancer, but the second leading cause of cancer death,
in the world, with more than 700,000 fatalities annually. The major etiology of liver cancer is …

Fucosylation is the process of transferring fucose from GDP-fucose to their substrates, which
includes certain proteins, N-and O-linked glycans in glycoprotein or glycolipids, by …

Changes in glycosylation readily occur in cancer and other disease states. Thanks to recent
advances in the development of analytical techniques and instrumentation, especially in …

Several studies suggest that variations in the concentration of plasma glycoproteins can
influence cellular changes in a large number of diseases. In recent years, proton nuclear …

Highlights•Aberrant fucosylation is a signature of malignant cell transformation and
modulates the occurrence and development of cancer.•Targeting fucosyltransferases (FUTs) …

Hepatocellular carcinoma (HCC), one of the leading causes of cancer deaths in the world, is
offering a challenge to human beings, with the current modes of treatment being a palliative …