Miniaturization of NMR systems: Desktop spectrometers, microcoil spectroscopy, and “NMR on a chip” for chemistry, biochemistry, and industry

SS Zalesskiy, E Danieli, B Blumich… - Chemical …, 2014 - ACS Publications
Nuclear magnetic resonance spectroscopy (NMR) nowadays is one of the most powerful
and versatile analytical methods for modern organic chemistry,(1) catalysis,(2) biology,(3) …

Analytical pitfalls and challenges in clinical metabolomics

I Kohler, A Verhoeven, RJE Derks, M Giera - Bioanalysis, 2016 - Taylor & Francis
Metabolomics-based strategies have become an integral part of modern clinical research,
allowing for a better understanding of pathophysiological conditions and disease …

[HTML][HTML] 代谢组学研究进展

许国旺, 路鑫, 杨胜利 - 中国医学科学院学报, 2007 - journal13.magtechjournal.com
代谢组学是功能基因组学和系统生物学研究不可或缺的重要组成部分, 是通过考察生物体系受
刺激或扰动前后(如将某个特定的基因变异或环境变化后) 代谢产物的动态变化 …

Metabolic signatures of lung cancer in biofluids: NMR-based metabonomics of blood plasma

CM Rocha, J Carrola, AS Barros, AM Gil… - Journal of proteome …, 2011 - ACS Publications
In this work, the variations in the metabolic profile of blood plasma from lung cancer patients
and healthy controls were investigated through NMR-based metabonomics, to assess the …

Advancing NMR sensitivity for LC-NMR-MS using a cryoflow probe: application to the analysis of acetaminophen metabolites in urine

M Spraul, AS Freund, RE Nast, RS Withers… - Analytical …, 2003 - ACS Publications
Cryogenic cooling of the NMR radio frequency coils and electronics to give greatly
enhanced sensitivity is arguably the most significant recent advance in NMR spectroscopy …

Diffusion and relaxation edited proton NMR spectroscopy of plasma reveals a high-fidelity supramolecular biomarker signature of SARS-CoV-2 infection

S Lodge, P Nitschke, T Kimhofer, J Wist… - Analytical …, 2021 - ACS Publications
We have applied nuclear magnetic resonance spectroscopy based plasma phenotyping to
reveal diagnostic molecular signatures of SARS-CoV-2 infection via combined diffusional …

NMR metabolic profile of human follicular fluid

E Piñero‐Sagredo, S Nunes… - NMR in …, 2010 - Wiley Online Library
The environment of the oocyte during its in vivo maturation consists of follicular fluid (FF) and
is surrounded by granulosa cells. The FF is derived from the sanguineous plasma and …

Use of 1H NMR‐determined diffusion coefficients to characterize lipoprotein fractions in human blood plasma

M Liu, H Tang, JK Nicholson… - Magnetic Resonance in …, 2002 - Wiley Online Library
The 1H NMR spectra of human blood plasma show, inter alia, prominent resonances from
the methyl and methylene groups of the fatty acyl chains from the triglycerides …

Statistical correlation and projection methods for improved information recovery from diffusion-edited NMR spectra of biological samples

LM Smith, AD Maher, O Cloarec… - Analytical …, 2007 - ACS Publications
Although NMR spectroscopic techniques coupled with multivariate statistics can yield much
useful information for classifying biological samples based on metabolic profiles, biomarker …

Analysis of lipoproteins using 2D diffusion-edited NMR spectroscopy and multi-way chemometrics

M Dyrby, M Petersen, AK Whittaker, L Lambert… - Analytica Chimica …, 2005 - Elsevier
This study represents the first application of multi-way calibration by N-PLS and multi-way
curve resolution by PARAFAC to 2D diffusion-edited 1H NMR spectra. The aim of the …