Mitochondrial fusion, fission, and mitochondrial toxicity

JN Meyer, TC Leuthner, AL Luz - Toxicology, 2017 - Elsevier
Mitochondrial dynamics are regulated by two sets of opposed processes: mitochondrial
fusion and fission, and mitochondrial biogenesis and degradation (including mitophagy), as …

Mitochondria in skin health, aging, and disease

A Sreedhar, L Aguilera-Aguirre, KK Singh - Cell death & disease, 2020 - nature.com
The skin is a high turnover organ, and its constant renewal depends on the rapid
proliferation of its progenitor cells. The energy requirement for these metabolically active …

[HTML][HTML] A systematic review on advances in management of oxidative stress-associated cardiovascular diseases

S Jin, PM Kang - Antioxidants, 2024 - mdpi.com
Oxidative stress plays a significant role in the pathogenesis of cardiovascular diseases, such
as myocardial ischemia/reperfusion injury, atherosclerosis, heart failure, and hypertension …

The role of mitochondrial quality surveillance in skin aging: focus on mitochondrial dynamics, biogenesis and mitophagy

C Zhang, X Gao, M Li, X Yu, F Huang, Y Wang… - Ageing research …, 2023 - Elsevier
The skin is the largest organ of the human body and the first line of defense against
environmental hazards. Many factors, including internal factors such as natural aging and …

A deep dive into UV-based phototherapy: Mechanisms of action and emerging molecular targets in inflammation and cancer

PA Vieyra-Garcia, P Wolf - Pharmacology & therapeutics, 2021 - Elsevier
UV-based phototherapy (including psoralen plus UVA (PUVA), UVB and UVA1) has a long,
successful history in the management of numerous cutaneous disorders. Photoresponsive …

Mitochondrial morphology is associated with respiratory chain uncoupling in autism spectrum disorder

RE Frye, L Lionnard, I Singh, MA Karim… - Translational …, 2021 - nature.com
Autism spectrum disorder (ASD) is a neurodevelopmental disorder that is associated with
unique changes in mitochondrial metabolism, including elevated respiration rates and …

Autophagy contributes to the quality control of leaf mitochondria

S Nakamura, S Hagihara, K Otomo… - Plant and Cell …, 2021 - academic.oup.com
In autophagy, cytoplasmic components of eukaryotic cells are transported to lysosomes or
the vacuole for degradation. Autophagy is involved in plant tolerance to the photooxidative …

[HTML][HTML] Role of mitochondria on UV-induced skin damage and molecular mechanisms of active chemical compounds targeting mitochondria

H He, L Xiong, L Jian, L Li, Y Wu, S Qiao - Journal of Photochemistry and …, 2022 - Elsevier
Mitochondria are the principal place of energy metabolism and ROS production, leading to
mtDNA being especially sensitive to the impacts of oxidative stress. Our review aims to …

The underestimated role of mitochondria in vitiligo: From oxidative stress to inflammation and cell death

Y Lin, Y Ding, Y Wu, Y Yang, Z Liu… - Experimental …, 2024 - Wiley Online Library
Vitiligo is an acquired depigmentary disorder characterized by the depletion of melanocytes
in the skin. Mitochondria shoulder multiple functions in cells, such as production of ATP …

PARP1 inhibition augments UVB-mediated mitochondrial changes—implications for UV-induced DNA repair and photocarcinogenesis

C Hegedűs, G Boros, E Fidrus, GN Kis, M Antal… - Cancers, 2019 - mdpi.com
Keratinocytes provide the first line of defense of the human body against carcinogenic
ultraviolet (UV) radiation. Acute and chronic UVB-mediated cellular responses were widely …