Venom systems as models for studying the origin and regulation of evolutionary novelties
G Zancolli, NR Casewell - Molecular Biology and Evolution, 2020 - academic.oup.com
A central goal in biology is to determine the ways in which evolution repeats itself. One of the
most remarkable examples in nature of convergent evolutionary novelty is animal venom …
most remarkable examples in nature of convergent evolutionary novelty is animal venom …
Sea anemones: Quiet achievers in the field of peptide toxins
Sea anemones have been understudied as a source of peptide and protein toxins, with
relatively few examined as a source of new pharmacological tools or therapeutic leads. This …
relatively few examined as a source of new pharmacological tools or therapeutic leads. This …
Sea anemone toxins: A structural overview
Sea anemones produce venoms of exceptional molecular diversity, with at least 17 different
molecular scaffolds reported to date. These venom components have traditionally been …
molecular scaffolds reported to date. These venom components have traditionally been …
Dynamics of venom composition across a complex life cycle
Little is known about venom in young developmental stages of animals. The appearance of
toxins and stinging cells during early embryonic stages in the sea anemone Nematostella …
toxins and stinging cells during early embryonic stages in the sea anemone Nematostella …
The assassin bug Pristhesancus plagipennis produces two distinct venoms in separate gland lumens
The assassin bug venom system plays diverse roles in prey capture, defence and extra-oral
digestion, but it is poorly characterised, partly due to its anatomical complexity. Here we …
digestion, but it is poorly characterised, partly due to its anatomical complexity. Here we …
Revisiting venom of the sea anemone Stichodactyla haddoni: Omics techniques reveal the complete toxin arsenal of a well-studied sea anemone genus
More than a century of research on sea anemone venoms has shown that they contain a
diversity of biologically active proteins and peptides. However, recent omics studies have …
diversity of biologically active proteins and peptides. However, recent omics studies have …
Venoms for all occasions: the functional toxin profiles of different anatomical regions in sea anemones are related to their ecological function
The phylum Cnidaria is the oldest extant venomous group and is defined by the presence of
nematocysts, specialized organelles responsible for venom production and delivery …
nematocysts, specialized organelles responsible for venom production and delivery …
Sea anemone venom: Ecological interactions and bioactive potential
This article provides a brief overview of the literature related to the chemical ecology of sea
anemones, focusing on their venom, and summarizing their bioprospecting potential. Sea …
anemones, focusing on their venom, and summarizing their bioprospecting potential. Sea …
The Birth and Death of Toxins with Distinct Functions: A Case Study in the Sea Anemone Nematostella
MY Sachkova, SA Singer, J Macrander… - Molecular Biology …, 2019 - academic.oup.com
The cnidarian Nematostella vectensis has become an established lab model, providing
unique opportunities for venom evolution research. The Nematostella venom system is …
unique opportunities for venom evolution research. The Nematostella venom system is …
Modern venomics—Current insights, novel methods, and future perspectives in biological and applied animal venom research
BM von Reumont, G Anderluh, A Antunes… - …, 2022 - academic.oup.com
Venoms have evolved> 100 times in all major animal groups, and their components, known
as toxins, have been fine-tuned over millions of years into highly effective biochemical …
as toxins, have been fine-tuned over millions of years into highly effective biochemical …