Venom systems as models for studying the origin and regulation of evolutionary novelties

G Zancolli, NR Casewell - Molecular Biology and Evolution, 2020 - academic.oup.com
A central goal in biology is to determine the ways in which evolution repeats itself. One of the
most remarkable examples in nature of convergent evolutionary novelty is animal venom …

Sea anemones: Quiet achievers in the field of peptide toxins

P J. Prentis, A Pavasovic, R S. Norton - Toxins, 2018 - mdpi.com
Sea anemones have been understudied as a source of peptide and protein toxins, with
relatively few examined as a source of new pharmacological tools or therapeutic leads. This …

Sea anemone toxins: A structural overview

B Madio, GF King, EAB Undheim - Marine drugs, 2019 - mdpi.com
Sea anemones produce venoms of exceptional molecular diversity, with at least 17 different
molecular scaffolds reported to date. These venom components have traditionally been …

Dynamics of venom composition across a complex life cycle

YY Columbus-Shenkar, MY Sachkova, J Macrander… - Elife, 2018 - elifesciences.org
Little is known about venom in young developmental stages of animals. The appearance of
toxins and stinging cells during early embryonic stages in the sea anemone Nematostella …

The assassin bug Pristhesancus plagipennis produces two distinct venoms in separate gland lumens

AA Walker, ML Mayhew, J Jin, V Herzig… - Nature …, 2018 - nature.com
The assassin bug venom system plays diverse roles in prey capture, defence and extra-oral
digestion, but it is poorly characterised, partly due to its anatomical complexity. Here we …

Revisiting venom of the sea anemone Stichodactyla haddoni: Omics techniques reveal the complete toxin arsenal of a well-studied sea anemone genus

B Madio, EAB Undheim, GF King - Journal of Proteomics, 2017 - Elsevier
More than a century of research on sea anemone venoms has shown that they contain a
diversity of biologically active proteins and peptides. However, recent omics studies have …

Venoms for all occasions: the functional toxin profiles of different anatomical regions in sea anemones are related to their ecological function

LM Ashwood, EAB Undheim, B Madio… - Molecular …, 2022 - Wiley Online Library
The phylum Cnidaria is the oldest extant venomous group and is defined by the presence of
nematocysts, specialized organelles responsible for venom production and delivery …

Sea anemone venom: Ecological interactions and bioactive potential

C Menezes, NL Thakur - Toxicon, 2022 - Elsevier
This article provides a brief overview of the literature related to the chemical ecology of sea
anemones, focusing on their venom, and summarizing their bioprospecting potential. Sea …

The Birth and Death of Toxins with Distinct Functions: A Case Study in the Sea Anemone Nematostella

MY Sachkova, SA Singer, J Macrander… - Molecular Biology …, 2019 - academic.oup.com
The cnidarian Nematostella vectensis has become an established lab model, providing
unique opportunities for venom evolution research. The Nematostella venom system is …

Modern venomics—Current insights, novel methods, and future perspectives in biological and applied animal venom research

BM von Reumont, G Anderluh, A Antunes… - …, 2022 - academic.oup.com
Venoms have evolved> 100 times in all major animal groups, and their components, known
as toxins, have been fine-tuned over millions of years into highly effective biochemical …