[HTML][HTML] The degree of frailty as a translational measure of health in aging

SE Howlett, AD Rutenberg, K Rockwood - Nature Aging, 2021 - nature.com
Frailty is a multiply determined, age-related state of increased risk for adverse health
outcomes. We review how the degree of frailty conditions the development of late-life …

[HTML][HTML] Frailty-aware care: giving value to frailty assessment across different healthcare settings

KF Boreskie, JL Hay, PE Boreskie, RC Arora… - BMC geriatrics, 2022 - Springer
Healthcare systems need to adapt to better serve an aging population with complex
presentations. Frailty assessments are a potential means to address this heterogeneity in …

Frailty, a multisystem ageing syndrome

J Thillainadesan, IA Scott, DG Le Couteur - Age and ageing, 2020 - academic.oup.com
The management of frail older people is a key component of aged care. There has been a
plethora of tools developed for the diagnosis and screening of frailty. Some of these tools …

Frailty is associated with postoperative delirium but not with postoperative cognitive decline in older noncardiac surgery patients

E Mahanna-Gabrielli, K Zhang, FE Sieber… - Anesthesia & …, 2020 - journals.lww.com
BACKGROUND: Postoperative cognitive dysfunction (POCD) and delirium are the most
common perioperative cognitive complications in older adults undergoing surgery. A recent …

Accumulation of deficits as a key risk factor for cardiovascular morbidity and mortality: a pooled analysis of 154 000 individuals

MAM Farooqi, H Gerstein, S Yusuf… - Journal of the American …, 2020 - Am Heart Assoc
Background Frailty is associated with higher mortality in individuals at high cardiovascular
disease (CVD) risk. We hypothesize that frailty is a more important prognostic factor than …

Nutrition and frailty: Current knowledge

C Feart - Progress in Neuro-Psychopharmacology and …, 2019 - Elsevier
Purpose of the review Nutrition, as part of lifestyle and modifiable environmental factors,
constitutes an interesting approach for the prevention of geriatric syndromes. The objective …

[HTML][HTML] Healthy behaviors at age 50 years and frailty at older ages in a 20-year follow-up of the UK Whitehall II cohort: A longitudinal study

A Gil-Salcedo, A Dugravot, A Fayosse… - PLoS …, 2020 - journals.plos.org
Background Frailty is associated with increased risk of various health conditions, disability,
and death. Health behaviors are thought to be a potential target for frailty prevention, but the …

[HTML][HTML] Association of frailty with the incidence risk of cardiovascular disease and type 2 diabetes mellitus in long-term cancer survivors: a prospective cohort study

X Cao, Z Yang, X Li, C Chen, EO Hoogendijk, J Zhang… - BMC medicine, 2023 - Springer
Background Comorbidities among cancer survivors remain a serious healthcare burden and
require appropriate management. Using two widely used frailty indicators, this study aimed …

What is an aging-related disease? An epidemiological perspective

DG Le Couteur, J Thillainadesan - The Journals of Gerontology …, 2022 - academic.oup.com
There are no established or standardized definitions of aging-related disease. Data from the
Global Burden of Diseases, Injuries, and Risk Factors Study 2019 were used to model the …

[HTML][HTML] Frailty index and cardiovascular disease among middle-aged and older Chinese adults: a nationally representative cross-sectional and follow-up study

X Liu, G Dai, Q He, H Ma, H Hu - Journal of cardiovascular development …, 2022 - mdpi.com
Evidence for the association between the frailty index and cardiovascular disease (CVD) is
inconclusive, and this association has not been evaluated in Chinese adults. We aim to …