During spaceflight, the central nervous system (CNS) is exposed to a complex array of
environmental stressors. However, the effects of long-duration spaceflight on the CNS and …

Microgravity, confinement, isolation, and immobilization are just some of the features
astronauts have to cope with during space missions. Consequently, long-duration space …

As human space exploration advances to establish a permanent presence beyond the Low
Earth Orbit (LEO) with NASA's Artemis mission, researchers are striving to understand and …

Emerging plans for travel to Mars and other deep space destinations make it critical for us to
understand how spaceflight affects the human brain and behavior. Research over the past …

The response of the human body to multiple spaceflight stressors is complex, but mounting
evidence implicate risks to CNS functionality as significant, able to threaten metrics of …

The present study reports alterations of task-based functional brain connectivity in a group of
11 cosmonauts after a long-duration spaceflight, compared to a healthy control group not …

The environment on the space station is quite unique compared to Earth, which is a
composite of multiple stressors, such as microgravity, isolation, confinement, noise …

Background Adverse effects of spaceflight on sensorimotor function have been linked to
altered somatosensory and vestibular inputs in the microgravity environment. Whether these …

Orthostatic challenge produced by upright posture may lead to syncope if the cardiovascular
system is unable to maintain adequate brain perfusion. This review outlines orthostatic …

Abstract Rationale and Hypothesis Advancements in technology, human adaptability, and
funding have increased space exploration and in turn commercial spaceflight. Corporations …