Phosphorus-based organocatalysis encompasses several subfields that have undergone
rapid growth in recent years. This Outlook gives an overview of its various aspects. In …

The synthesis of phosphorus molecules presenting a chiral center on the P‐atom, also
known as P‐stereogenic compounds, has long attracted the curiosity of the scientific …

The practical synthesis of P-stereogenic tertiary phosphines, which have wide applications
in asymmetric catalysis, materials, and pharmaceutical chemistry, represents a significant …

Alkenylphosphine oxides have a wide spectrum of practical applications. However, chemo‐,
regio‐, and enantiocontrolled construction of this structural motif still constitutes a significant …

The catalytic asymmetric synthesis of P‐chiral phosphorus compounds is an important way
to construct P‐chiral ligands. Herein, we report a new strategy that adopts the pyridinyl …

A nickel-catalyzed asymmetric allylation of secondary phosphine oxides (SPO) for the
synthesis of tertiary phosphine oxides (TPO) was realized with high enantioselectivity. The …

The catalytic asymmetric synthesis of P-stereogenic phosphines is an efficient strategy to
access structurally diverse chiral phosphines that could serve as organocatalysts and …

The synthesis of P-stereogenic building blocks is extremely difficult. Herein we report an
efficient kinetic resolution of secondary phosphine oxides via a Le-Phos-catalyzed …

A nickel-catalyzed benzylic substitution of secondary phosphine oxide was described,
affording the dialkylated P-stereogenic tertiary phosphine oxides with high to excellent …

The asymmetric synthesis of P-stereogenic phosphinates through allylic alkylation of H-
phosphinates has been developed. With H-phosphinates and allylic acetates as the starting …