Our knowledge of pluripotent stem cell (PSC) biology has advanced to the point where we
now can generate most cells of the human body in the laboratory. PSC-derived …

Results obtained from completed and on-going clinical studies indicate huge therapeutic
potential of stem cell-based therapy in the treatment of degenerative, autoimmune and …

Human cardiac organoids hold remarkable potential for cardiovascular disease modeling
and human pluripotent stem cell–derived cardiomyocyte (hPSC-CM) transplantation. Here …

Induced pluripotent stem cells (iPSCs) constitute a potential source of autologous patient-
specific cardiomyocytes for cardiac repair, providing a major benefit over other sources of …

Human embryonic stem cell-derived cardiomyocytes (hESC-CMs) show considerable
promise for regenerating injured hearts, and we therefore tested their capacity to stably …

Pluripotent stem cells provide a potential solution to current epidemic rates of heart failure by
providing human cardiomyocytes to support heart regeneration. Studies of human …

A large number of clinical trials have shown stem cell therapy to be a promising therapeutic
approach for the treatment of cardiovascular diseases. Since the first transplantation into …

Despite preclinical studies demonstrating the functional benefit of transplanting human
pluripotent stem cell-derived cardiomyocytes (PSC-CMs) into damaged myocardium, the …

Transplantation studies in mice and rats have shown that human embryonic-stem-cell-
derived cardiomyocytes (hESC-CMs) can improve the function of infarcted hearts,,, but two …

Cardiomyocytes derived from human embryonic stem (hES) cells potentially offer large
numbers of cells to facilitate repair of the infarcted heart. However, this approach has been …