The reactive oxygen species (ROS)-mediated mechanism is the major cause underlying the
efficacy of photodynamic therapy (PDT). The PDT procedure is based on the cascade of …

Glycogen synthase kinase-3β (GSK-3β) is an evolutionarily conserved serine/threonine
kinase, functioning in numerous cellular processes including cell proliferation, DNA repair …

The repair of DNA damage is a complex process that relies on particular pathways to
remedy specific types of damage to DNA. The range of insults to DNA includes small …

Radiotherapy is one of the major therapeutic strategies for cancer treatment. In the past
decade, there has been growing interest in using high Z (atomic number) elements …

Achieving effective treatment of deep-seated tumors is a major challenge for traditional
photodynamic therapy (PDT) due to difficulties in delivering light into the subsurface. Thanks …

Cisplatin-based treatment is the first line chemotherapy for several cancers including
ovarian cancer. The development of cisplatin resistance results in treatment failure, but the …

Cancer is a genetic disorder that results from genetic or epigenetic alterations in the somatic
cells and has abnormal cell growth which may be spread to other body parts. In 2018, 18 …

Cisplatin (cis-diamminedichloroplatinum (II)) is the oldest known chemotherapeutic agent.
Since the identification of its anti-tumour activity, it earned a remarkable place as a treatment …

This report presents the recommendations of the WHO Expert Committee responsible for
updating the WHO Model Lists of Essential Medicines.. The goal of the meeting was to …

Background Human papillomavirus (HPV) is the most identifiable cause of head and neck
squamous cell cancer (HNSCC). Compared with HPV-negative HNSCC, HPV-positive …