Glial cells: role of the immune response in ischemic stroke
S Xu, J Lu, A Shao, JH Zhang, J Zhang - Frontiers in immunology, 2020 - frontiersin.org
Ischemic stroke, which accounts for 75–80% of all strokes, is the predominant cause of
morbidity and mortality worldwide. The post-stroke immune response has recently emerged …
morbidity and mortality worldwide. The post-stroke immune response has recently emerged …
Blood-brain barrier dysfunction and recovery after ischemic stroke
The blood-brain barrier (BBB) plays a vital role in regulating the trafficking of fluid, solutes
and cells at the blood-brain interface and maintaining the homeostatic microenvironment of …
and cells at the blood-brain interface and maintaining the homeostatic microenvironment of …
Fluorescence-amplified nanocrystals in the second near-infrared window for in vivo real-time dynamic multiplexed imaging
Optical imaging in the second near-infrared window (NIR-II, 1,000–1,700 nm) holds great
promise for non-invasive in vivo detection. However, real-time dynamic multiplexed imaging …
promise for non-invasive in vivo detection. However, real-time dynamic multiplexed imaging …
Pathogenic mechanisms following ischemic stroke
Stroke is the second most common cause of death and the leading cause of disability
worldwide. Brain injury following stroke results from a complex series of pathophysiological …
worldwide. Brain injury following stroke results from a complex series of pathophysiological …
Cerebral vascular disease and neurovascular injury in ischemic stroke
The consequences of cerebrovascular disease are among the leading health issues
worldwide. Large and small cerebral vessel disease can trigger stroke and contribute to the …
worldwide. Large and small cerebral vessel disease can trigger stroke and contribute to the …
Commensal microbiota affects ischemic stroke outcome by regulating intestinal γδ T cells
Commensal gut bacteria impact the host immune system and can influence disease
processes in several organs, including the brain. However, it remains unclear whether the …
processes in several organs, including the brain. However, it remains unclear whether the …
[HTML][HTML] Implications of MMP9 for blood brain barrier disruption and hemorrhagic transformation following ischemic stroke
Numerous studies have documented increases in matrix metalloproteinases (MMPs),
specifically MMP-9 levels following stroke, with such perturbations associated with …
specifically MMP-9 levels following stroke, with such perturbations associated with …
Rapid endothelial cytoskeletal reorganization enables early blood–brain barrier disruption and long-term ischaemic reperfusion brain injury
The mechanism and long-term consequences of early blood–brain barrier (BBB) disruption
after cerebral ischaemic/reperfusion (I/R) injury are poorly understood. Here we discover …
after cerebral ischaemic/reperfusion (I/R) injury are poorly understood. Here we discover …
Microglial cell loss after ischemic stroke favors brain neutrophil accumulation
A Otxoa-de-Amezaga, F Miró-Mur, J Pedragosa… - Acta …, 2019 - Springer
Stroke attracts neutrophils to the injured brain tissue where they can damage the integrity of
the blood–brain barrier and exacerbate the lesion. However, the mechanisms involved in …
the blood–brain barrier and exacerbate the lesion. However, the mechanisms involved in …
Hemorrhagic transformation after ischemic stroke in animals and humans
GC Jickling, DZ Liu, B Stamova… - Journal of Cerebral …, 2014 - journals.sagepub.com
Hemorrhagic transformation (HT) is a common complication of ischemic stroke that is
exacerbated by thrombolytic therapy. Methods to better prevent, predict, and treat HT are …
exacerbated by thrombolytic therapy. Methods to better prevent, predict, and treat HT are …