Recent advances in next-generation sequencing technologies have brought a paradigm
shift in how medical researchers investigate both rare and common human disorders. The …

Despite extensive debate, there is no consensus on whether individual genetic data should
be disclosed to research participants. The emergence of whole-genome sequencing …

Biobanks and archived data sets collecting samples and data have become crucial engines
of genetic and genomic research. Unresolved, however, is what responsibilities biobanks …

In January 2009, the National Heart, Lung, and Blood Institute convened a 28-member
multidisciplinary Working Group to update the recommendations of a 2004 National Heart …

Background Profound knowledge about child growth, development, health, and disease in
contemporary children and adolescents is still rare. Epidemiological studies together with …

The National Institutes of Health and other federal health agencies are considering
establishing a national biobank to study the roles of genes and environment in human …

Communicating the Results of Clinical Research to Participants: Attitudes, Practices, and Future
Directions | PLOS Medicine Skip to main content Advertisement PLOS Medicine Browse Current …

Any test that produces visual images or digital or genetic sequences will tend to produce
incidental findings because more will be visible than what was originally sought. We …

The recent completion of the first two individual whole-genome sequences is a research
milestone. As personal genome research advances, investigators and international research …

Genetic discrimination (GD) is a complex, multifaceted ethical, psychosocial, and legal
phenomenon. It is defined as the differential treatment of asymptomatic individuals or their …