[HTML][HTML] The role and specific mechanism of OCT4 in cancer stem cells: a review
Q Zhang, Z Han, Y Zhu, J Chen… - International journal of …, 2020 - synapse.koreamed.org
Recently, evidences show that cancer stem cells (CSCs) are a type of cancer cell group with
self-renewal and play a huge role in tumor recurrence, metastasis, and drug resistance …
self-renewal and play a huge role in tumor recurrence, metastasis, and drug resistance …
Prevention of tumor risk associated with the reprogramming of human pluripotent stem cells
K Wuputra, CC Ku, DC Wu, YC Lin, S Saito… - Journal of Experimental …, 2020 - Springer
Human pluripotent embryonic stem cells have two special features: self-renewal and
pluripotency. It is important to understand the properties of pluripotent stem cells and …
pluripotency. It is important to understand the properties of pluripotent stem cells and …
[HTML][HTML] Stemness-related markers in cancer
Cancer stem cells (CSCs), with their self-renewal ability and multilineage differentiation
potential, are a critical subpopulation of tumor cells that can drive tumor initiation, growth …
potential, are a critical subpopulation of tumor cells that can drive tumor initiation, growth …
Roles of OCT4 in tumorigenesis, cancer therapy resistance and prognosis
Abstract OCT4 (POU5F1) is a major regulator of cell pluripotency and plays an important
role not only during embryogenesis but also in tumorigenesis. It has been studied in various …
role not only during embryogenesis but also in tumorigenesis. It has been studied in various …
Hypoxia-induced cancer cell reprogramming: a review on how cancer stem cells arise
Cancer stem cells are a subset of cells within the tumor that possess the ability to self-renew
as well as differentiate into different cancer cell lineages. The exact mechanisms by which …
as well as differentiate into different cancer cell lineages. The exact mechanisms by which …
Cancer stem cell detection and isolation
M Moghbeli, F Moghbeli, MM Forghanifard… - Medical Oncology, 2014 - Springer
Only 10% of cancer-related deaths result from primary tumors; most are caused by
metastatic tumors. It is believed that the metastatic power of tumor cells is attributed to …
metastatic tumors. It is believed that the metastatic power of tumor cells is attributed to …
Cytokeratin 19 (KRT19) has a Role in the Reprogramming of Cancer Stem Cell-Like Cells to Less Aggressive and More Drug-Sensitive Cells
Cytokeratin 19 (KRT19) is a cytoplasmic intermediate filament protein, which is responsible
for structural rigidity and multipurpose scaffolds. In several cancers, KRT19 is overexpressed …
for structural rigidity and multipurpose scaffolds. In several cancers, KRT19 is overexpressed …
[HTML][HTML] Decreased TRPM7 inhibits activities and induces apoptosis of bladder cancer cells via ERK1/2 pathway
R Cao, Z Meng, T Liu, G Wang, G Qian, T Cao… - Oncotarget, 2016 - ncbi.nlm.nih.gov
Transient receptor potential melastatin 7 (TRPM7) functions as a Mg 2+/Ca 2+-permeable
channel fused with a kinase domain and regulates various physical processes and …
channel fused with a kinase domain and regulates various physical processes and …
Tumor microenvironment: A niche for cancer stem cell immunotherapy
Abstract Tumorigenic Cancer Stem Cells (CSCs), often called tumor-initiating cells (TICs),
represent a unique subset of cells within the tumor milieu. They stand apart from the bulk of …
represent a unique subset of cells within the tumor milieu. They stand apart from the bulk of …
OCT4 but not SOX2 expression correlates with worse prognosis in surgical patients with triple-negative breast cancer
JM Zhang, K Wei, M Jiang - Breast Cancer, 2018 - Springer
Background Octamer-binding transcription factor 4 (OCT4) and SRY (sex determining region
Y)-box 2 (SOX2) are common biomarkers of cancer stem cells, which contribute to the …
Y)-box 2 (SOX2) are common biomarkers of cancer stem cells, which contribute to the …