Metabolic regulation of skeletal cell fate and function
S Stegen, G Carmeliet - Nature Reviews Endocrinology, 2024 - nature.com
Bone development and bone remodelling during adult life are highly anabolic processes
requiring an adequate supply of oxygen and nutrients. Bone-forming osteoblasts and bone …
requiring an adequate supply of oxygen and nutrients. Bone-forming osteoblasts and bone …
Cross-talk of inflammation and chondrocyte intracellular metabolism in osteoarthritis
M Arra, Y Abu-Amer - Osteoarthritis and Cartilage, 2023 - Elsevier
Osteoarthritis is a disease that impacts millions around the world, leading to significant
financial and medical burden for patients and the healthcare system. However, no effective …
financial and medical burden for patients and the healthcare system. However, no effective …
Comparative pharyngeal cartilage developmental toxicity of bisphenol A, bisphenol S and bisphenol AF to zebrafish (Danio rerio) larvae: A combination of …
W Huang, X Shi, Y Chen, Q Zhang, J Peng… - Science of the Total …, 2023 - Elsevier
Exposure to BPA is recently shown to affect cartilage development in teleost fishes; whether
BPS and BPAF, its two most frequently used phenolic analogues have similar effect …
BPS and BPAF, its two most frequently used phenolic analogues have similar effect …
Diabetes mellitus in rheumatic diseases: clinical characteristics and treatment considerations
Y Fedorchenko, K Mahmudov, Z Abenov… - Rheumatology …, 2023 - Springer
New pathophysiological insights are now available on comorbidities in rheumatic diseases
(RDs). Several nationwide studies point to the fact that comorbid diabetes mellitus (DM) …
(RDs). Several nationwide studies point to the fact that comorbid diabetes mellitus (DM) …
Fructose-bisphosphatase1 (FBP1) alleviates experimental osteoarthritis by regulating Protein crumbs homolog 3 (CRB3)
Z Wang, X Wang, L Liu, X Guo, H Zhang, J Yin… - Arthritis Research & …, 2023 - Springer
Purpose To identify the role of gluconeogenesis in chondrocytes in osteoarthritis (OA).
Materials and methods Cartilage samples were collected from OA patients and C57 mice …
Materials and methods Cartilage samples were collected from OA patients and C57 mice …
Metabolic syndrome increases osteoarthritis risk: findings from the UK Biobank prospective cohort study
S Zhang, D Wang, J Zhao, H Zhao, P Xie, L Zheng… - BMC Public Health, 2024 - Springer
Abstract Objective The association between Metabolic Syndrome (MetS), its components,
and the risk of osteoarthritis (OA) has been a topic of conflicting evidence in different studies …
and the risk of osteoarthritis (OA) has been a topic of conflicting evidence in different studies …
[HTML][HTML] Osteoarthritis year in review 2023: Biology
AJ Roelofs, C De Bari - Osteoarthritis and cartilage, 2023 - Elsevier
Great progress continues to be made in our understanding of the multiple facets of
osteoarthritis (OA) biology. Here, we review the major advances in this field and progress …
osteoarthritis (OA) biology. Here, we review the major advances in this field and progress …
Pyruvate Dehydrogenase Kinase 1 inhibition mediated oxidative phosphorylation enhancement in cartilage promotes osteoarthritis progression
X Yang, Q Jiang, T Luan, C Yu, Z Liu, T Wang… - BMC Musculoskeletal …, 2023 - Springer
Osteoarthritis (OA) is a common disease characterized by cartilage degradation. Growing
evidence showed that glucose metabolism impacts joint homeostasis and an imbalance …
evidence showed that glucose metabolism impacts joint homeostasis and an imbalance …
The role of targeting glucose metabolism in chondrocytes in the pathogenesis and therapeutic mechanisms of osteoarthritis: a narrative review
P Pi, L Zeng, Z Zeng, K Zong, B Han, X Bai… - Frontiers in …, 2024 - frontiersin.org
Osteoarthritis (OA) is a common degenerative joint disease that can affect almost any joint,
mainly resulting in joint dysfunction and pain. Worldwide, OA affects more than 240 million …
mainly resulting in joint dysfunction and pain. Worldwide, OA affects more than 240 million …
Triglyceride-glucose index in the prediction of new-onset arthritis in the general population aged over 45: the first longitudinal evidence from CHARLS
Y Liu, J Yao, X Xue, Y Lv, S Guo, PD Wei - Lipids in Health and Disease, 2024 - Springer
Objective Insulin resistance (IR) imposes a significant burden on inflammatory diseases, and
the triglyceride-glucose (TyG) index, which is an easily accessible indicator for detecting IR …
the triglyceride-glucose (TyG) index, which is an easily accessible indicator for detecting IR …